Intracellular persister: A stealth agent recalcitrant to antibiotics.

Autor:	Personnic N; CIRI, Centre International de Recherche en Infectiologie, CNRS UMR 5308, INSERM U1111, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.; Group Persistence and Single-Cell Dynamics of Respiratory Pathogens, Lyon, France., Doublet P; CIRI, Centre International de Recherche en Infectiologie, CNRS UMR 5308, INSERM U1111, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.; Group Legionella Pathogenesis, Lyon, France., Jarraud S; CIRI, Centre International de Recherche en Infectiologie, CNRS UMR 5308, INSERM U1111, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.; Group Legionella Pathogenesis, Lyon, France.; National Reference Centre for Legionella, Institute of Infectious Agents, Hospices Civils de Lyon, Lyon, France.
Jazyk:	angličtina
Zdroj:	Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Mar 31; Vol. 13, pp. 1141868. Date of Electronic Publication: 2023 Mar 31 (Print Publication: 2023).
DOI:	10.3389/fcimb.2023.1141868
Abstrakt:	The bulk of bacteria transiently evading appropriate antibiotic regimes and recovered from non-resolutive infections are commonly refer to as persisters. In this mini-review, we discuss how antibiotic persisters stem from the interplay between the pathogen and the cellular defenses mechanisms and its underlying heterogeneity. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Personnic, Doublet and Jarraud.)
Databáze:	MEDLINE
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