Interactions of Vibrio phages and their hosts in aquatic environments.

Autor: Molina-Quiroz RC; Stuart B. Levy Center for Integrated Management of Antimicrobial Resistance (Levy CIMAR), Tufts Medical Center and Tufts University, Boston, MA, USA., Silva-Valenzuela CA; Microbes Lab SpA, Valdivia, Los Ríos 5111038, Chile. Electronic address: cecilia@microbes-lab.com.
Jazyk: angličtina
Zdroj: Current opinion in microbiology [Curr Opin Microbiol] 2023 Aug; Vol. 74, pp. 102308. Date of Electronic Publication: 2023 Apr 14.
DOI: 10.1016/j.mib.2023.102308
Abstrakt: Bacteriophages (phages) are viruses that specifically infect bacteria. These viruses were discovered a century ago and have been used as a model system in microbial genetics and molecular biology. In order to survive, bacteria have to quickly adapt to phage challenges in their natural settings. In turn, phages continuously develop/evolve mechanisms for battling host defenses. A deeper understanding of the arms race between bacteria and phages is essential for the rational design of phage-based prophylaxis and therapies to prevent and treat bacterial infections. Vibrio species and their phages (vibriophages) are a suitable model to study these interactions. Phages are highly ubiquitous in aquatic environments and Vibrio are waterborne bacteria that must survive the constant attack by phages for successful transmission to their hosts. Here, we review relevant literature from the past two years to delve into the molecular interactions of Vibrio species and their phages in aquatic niches.
Competing Interests: Declaration of Competing Interest The authors have no conflicts of interest.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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