Open science and data sharing in cognitive neuroscience with MouseBytes and MouseBytes.

Autor: Memar S; BrainsCAN, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. smemarko@uwo.ca.; Robarts Research Institute, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. smemarko@uwo.ca., Jiang E; BrainsCAN, The University of Western Ontario, London, Ontario, N6A 3K7, Canada.; Robarts Research Institute, The University of Western Ontario, London, Ontario, N6A 3K7, Canada., Prado VF; BrainsCAN, The University of Western Ontario, London, Ontario, N6A 3K7, Canada.; Robarts Research Institute, The University of Western Ontario, London, Ontario, N6A 3K7, Canada.; Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario, N6A 3K7, Canada.; Department of Anatomy and Cell Biology, The University of Western Ontario, London, Ontario, N6A 3K7, Canada., Saksida LM; BrainsCAN, The University of Western Ontario, London, Ontario, N6A 3K7, Canada.; Robarts Research Institute, The University of Western Ontario, London, Ontario, N6A 3K7, Canada.; Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario, N6A 3K7, Canada., Bussey TJ; BrainsCAN, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. tbussey@uwo.ca.; Robarts Research Institute, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. tbussey@uwo.ca.; Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. tbussey@uwo.ca., Prado MAM; BrainsCAN, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. mprado@roarts.ca.; Robarts Research Institute, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. mprado@roarts.ca.; Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. mprado@roarts.ca.; Department of Anatomy and Cell Biology, The University of Western Ontario, London, Ontario, N6A 3K7, Canada. mprado@roarts.ca.
Jazyk: angličtina
Zdroj: Scientific data [Sci Data] 2023 Apr 14; Vol. 10 (1), pp. 210. Date of Electronic Publication: 2023 Apr 14.
DOI: 10.1038/s41597-023-02106-1
Abstrakt: Open access to rodent cognitive data has lagged behind the rapid generation of large open-access datasets in other areas of neuroscience, such as neuroimaging and genomics. One contributing factor has been the absence of uniform standardization in experiments and data output, an issue that has particularly plagued studies in animal models. Touchscreen-automated cognitive testing of animal models allows standardized outputs that are compatible with open-access sharing. Touchscreen datasets can be combined with different neuro-technologies such as fiber photometry, miniscopes, optogenetics, and MRI to evaluate the relationship between neural activity and behavior. Here we describe a platform that allows deposition of these data into an open-access repository. This platform, called MouseBytes, is a web-based repository that enables researchers to store, share, visualize, and analyze cognitive data. Here we present the architecture, structure, and the essential infrastructure behind MouseBytes. In addition, we describe MouseBytes+, a database that allows data from complementary neuro-technologies such as imaging and photometry to be easily integrated with behavioral data in MouseBytes to support multi-modal behavioral analysis.
(© 2023. The Author(s).)
Databáze: MEDLINE
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