Myocardial Scar Detection Using High-Resolution Free-Breathing 3D Dark-Blood and Standard Breath-Holding 2D Bright-Blood Late Gadolinium Enhancement MRI: A Comparison of Observer Confidence.

Autor:	Nies HMJM; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands., Martens B; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands., Gommers S; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands., Bijvoet GP; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.; Department of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands., Wildberger JE; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands., Ter Bekke RMA; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.; Department of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands., Holtackers RJ; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands., Mihl C; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.
Jazyk:	angličtina
Zdroj:	Topics in magnetic resonance imaging : TMRI [Top Magn Reson Imaging] 2023 Jun 01; Vol. 32 (3), pp. 27-32. Date of Electronic Publication: 2023 Apr 16.
DOI:	10.1097/RMR.0000000000000304
Abstrakt:	Objective: To compare observer confidence for myocardial scar detection using 3 different late gadolinium enhancement (LGE) data sets by 2 observers with different levels of experience. Materials and Methods: Forty-one consecutive patients, who were referred for 3D dark-blood LGE MRI before implantable cardioverter-defibrillator implantation or ablation therapy and who underwent 2D bright-blood LGE MRI within a time frame of 3 months, were prospectively included. From all 3D dark-blood LGE data sets, a stack of 2D short-axis slices was reconstructed. All acquired LGE data sets were anonymized and randomized and evaluated by 2 independent observers with different levels of experience in cardiovascular imaging (beginner and expert). Confidence in detection of ischemic scar, nonischemic scar, papillary muscle scar, and right ventricular scar for each LGE data set was scored using a using a 3-point Likert scale (1 = low, 2 = medium, or 3 = high). Observer confidence scores were compared using the Friedman omnibus test and Wilcoxon signed-rank post hoc test. Results: For the beginner observer, a significant difference in confidence regarding ischemic scar detection was observed in favor of reconstructed 2D dark-blood LGE compared with standard 2D bright-blood LGE (p = 0.030) while for the expert observer, no significant difference was found (p = 0.166). Similarly, for right ventricular scar detection, a significant difference in confidence was observed in favor of reconstructed 2D dark-blood LGE compared with standard 2D bright-blood LGE (p = 0.006) while for the expert observer, no significant difference was found (p = 0.662). Although not significantly different for other areas of interest, 3D dark-blood LGE and its derived 2D dark-blood LGE data set showed a tendency to score higher for all areas of interest at both experience levels. Conclusions: The combination of dark-blood LGE contrast and high isotropic voxels may contribute to increased observer confidence in myocardial scar detection, independent of observer's experience level but in particular for beginner observers. Competing Interests: The authors declare no conflict of interest. (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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