Finite element model of female thermoregulation with geometry based on medical images.

Autor: Castellani MP; Oak Ridge Institute for Science and Education (ORISE), USA; Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, USA. Electronic address: michael.p.castellani2.ctr@health.mil., Rioux TP; Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, USA., Castellani JW; Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, USA., Potter AW; Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, USA., Notley SR; Defence Science and Technology Group, Australia., Xu X; Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, USA. Electronic address: xiaojiang.xu.civ@health.mil.
Jazyk: angličtina
Zdroj: Journal of thermal biology [J Therm Biol] 2023 Apr; Vol. 113, pp. 103477. Date of Electronic Publication: 2023 Jan 08.
DOI: 10.1016/j.jtherbio.2023.103477
Abstrakt: Introduction: this study describes the development of a female finite element thermoregulatory model (FETM) METHOD: the female body model was developed from medical image datasets of a median U.S. female and was constructed to be anatomically correct. The body model preserves the geometric shapes of 13 organs and tissues, including skin, muscles, fat, bones, heart, lungs, brain, bladder, intestines, stomach, kidneys, liver, and eyes. Heat balance within the body is described by the bio-heat transfer equation. Heat exchange at the skin surface includes conduction, convection, radiation, and sweat evaporation. Vasodilation, vasoconstriction, sweating, and shivering are controlled by afferent and efferent signals to and from the skin and hypothalamus.
Results: the model was validated with measured physiological data during exercise and rest in thermoneutral, hot, and cold conditions. Validations show the model predicted the core temperature (rectal and tympanic temperatures) and mean skin temperatures with acceptable accuracy (within 0.5 °C and 1.6 °C, respectively) CONCLUSION: this female FETM predicted high spatial resolution temperature distribution across the female body, which provides quantitative insights into human thermoregulatory responses in females to non-uniform and transient environmental exposure.
Competing Interests: Declaration of competing interest The author declares that there are no conflicts of interest.
(Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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