A rare case of an extra-oral plasmablastic lymphoma presenting through a scrotal abscess in a 42-year-old man.

Autor: Śluzar P; King's College London, UK., Reekhaye A; Guy's and St Thomas' NHS Foundation Trust, UK., MacAskill F; King's College London, UK.; Guy's and St Thomas' NHS Foundation Trust, UK., Ong M; Guy's and St Thomas' NHS Foundation Trust, UK., Rose V; Guy's and St Thomas' NHS Foundation Trust, UK., Yap T; King's College London, UK.; Guy's and St Thomas' NHS Foundation Trust, UK.
Jazyk: angličtina
Zdroj: Annals of the Royal College of Surgeons of England [Ann R Coll Surg Engl] 2024 Apr; Vol. 106 (4), pp. 391-394. Date of Electronic Publication: 2023 Apr 13.
DOI: 10.1308/rcsann.2022.0166
Abstrakt: Plasmablastic lymphoma (PBL) is a rare lymphoid neoplasm frequently presenting in the oral cavity. It is an aggressive type of non-Hodgkin's lymphoma that shares pathological features with plasma cell myeloma. In addition to human immunodeficiency virus (HIV), it is also associated with Epstein-Bar virus (EBV) and immunosuppression in HIV-negative patients, for example, post transplantation. Extra-oral PBL is rare and only a few case reports involving the testis have been described. Here we describe the first reported case of PBL presenting with a scrotal abscess (not involving the testes) in a patient newly diagnosed with HIV. This case highlights the rare presentation of a rare disease, the difficulties in establishing a diagnosis and the importance of a timely multidisciplinary approach to its management.
Databáze: MEDLINE