Impact of a Cancer History on Cardiovascular Events Among Patients With Myocardial Infarction Who Received Revascularization.

Autor:	Takeuchi T; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Kosugi S; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Ueda Y; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Ikeoka K; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Yamane H; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Takayasu K; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Ohashi T; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Fukushima T; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Horiuchi K; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Iehara T; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Sakamoto M; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Ukai K; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Minami S; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Mizumori Y; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Muraoka N; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Nakamura M; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Ozaki T; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Mishima T; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Abe H; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Inoue K; Cardiovascular Division, National Hospital Organization Osaka National Hospital., Matsumura Y; Cardiovascular Division, National Hospital Organization Osaka National Hospital.
Jazyk:	angličtina
Zdroj:	Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2024 Jan 25; Vol. 88 (2), pp. 207-214. Date of Electronic Publication: 2023 Apr 12.
DOI:	10.1253/circj.CJ-22-0838
Abstrakt:	Background: It remains controversial whether a cancer history increases the risk of cardiovascular (CV) events among patients with myocardial infarction (MI) who undergo revascularization. Methods and results: Patients who were confirmed as type 1 acute MI (AMI) by coronary angiography were retrospectively analyzed. Patients who died in hospital or those not undergoing revascularization were excluded. Patients with a cancer history were compared with those without it. A cancer history was examined in the in-hospital cancer registry. The primary outcome was a composite of cardiac death, recurrent type 1 MI, post-discharge coronary revascularization, heart failure hospitalization, and stroke. Among 551 AMI patients, 55 had a cancer history (cancer group) and 496 did not (non-cancer group). Cox proportional hazards model revealed that the risk of composite endpoint was significantly higher in the cancer group than in the non-cancer group (adjusted hazard ratio [HR]: 1.78; 95% confidence interval [CI]: 1.13-2.82). Among the cancer group, patients who were diagnosed as AMI within 6 months after the cancer diagnosis had a higher risk of the composite endpoint than those who were diagnosed as AMI 6 months or later after the cancer diagnosis (adjusted HR: 5.43; 95% CI: 1.55-19.07). Conclusions: A cancer history increased the risk of CV events after discharge among AMI patients after revascularization.
Databáze:	MEDLINE
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