Magnetic resonance imaging of the knee for chronological age estimation-a systematic review.

Autor: Ording Muller LS; Division of Radiology and Nuclear Medicine, Department of Paediatric Radiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway. lilmul@ous-hf.no., Adolfsson J; Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, Sweden.; Department of Clinical Science, Intervention and Technology-CLINTEC, Karolinska Institutet, Stockholm, Sweden., Forsberg L; Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, Sweden.; Department of Clinical Science, Intervention and Technology-CLINTEC, Karolinska Institutet, Stockholm, Sweden., Bring J; Statisticon AB, Uppsala, Sweden., Dahlgren J; Department of Pediatrics, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Domeij H; Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, Sweden., Gornitzki C; Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, Sweden., Wernersson E; Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, Sweden., Odeberg J; Swedish Agency for Health Technology Assessment and Assessment of Social Services, Stockholm, Sweden.
Jazyk: angličtina
Zdroj: European radiology [Eur Radiol] 2023 Aug; Vol. 33 (8), pp. 5258-5268. Date of Electronic Publication: 2023 Apr 12.
DOI: 10.1007/s00330-023-09546-8
Abstrakt: Introduction: Radiographs of the hand and teeth are frequently used for medical age assessment, as skeletal and dental maturation correlates with chronological age. These methods have been criticized for their lack of precision, and magnetic resonance imaging (MRI) of the knee has been proposed as a more accurate method. The aim of this systematic review is to explore the scientific and statistical evidence for medical age estimation based on skeletal maturation as assessed by MRI of the knee.
Materials and Methods: A systematic review was conducted that included studies published before April 2021 on living individuals between 8 and 30 years old, with presumptively healthy knees for whom the ossification stages had been evaluated using MRI. The correlation between "mature knee" and chronological age and the risk of misclassifying a child as an adult and vice versa was calculated.
Results: We found a considerable heterogeneity in the published studies -in terms of study population, MRI protocols, and grading systems used. There is a wide variation in the correlation between maturation stage and chronological age.
Conclusion: Data from published literature is deemed too heterogenous to support the use of MRI of the knee for chronological age determination. Further, it is not possible to assess the sensitivity, specificity, negative predictive value, or positive predictive value for the ability of MRI to determine whether a person is over or under 18 years old.
Key Points: • There is an insufficient scientific basis for the use of magnetic resonance imaging of the knee in age determination by skeleton. • It is not possible to assess the predictive value of MRI of the knee to determine whether a person is over or under 18 years of age.
(© 2023. The Author(s).)
Databáze: MEDLINE
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