Genomic surveillance uncovers a pandemic clonal lineage of the wheat blast fungus.

Autor: Latorre SM; Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom., Were VM; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Foster AJ; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Langner T; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Malmgren A; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Harant A; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Asuke S; Graduate School of Agricultural Science, Kobe University, Kobe, Japan., Reyes-Avila S; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Gupta DR; Institute of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh., Jensen C; John Innes Centre, Norwich Research Park, Norwich, United Kingdom., Ma W; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Mahmud NU; Institute of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh., Mehebub MS; Institute of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh., Mulenga RM; Zambia Agricultural Research Institute, Mt. Makulu Central Research Station, Lusaka, Zambia., Muzahid ANM; Institute of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh., Paul SK; Institute of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh., Rabby SMF; Institute of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh., Rahat AAM; Institute of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh., Ryder L; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Shrestha RK; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Sichilima S; Zambia Agricultural Research Institute, Mt. Makulu Central Research Station, Lusaka, Zambia., Soanes DM; Department of Biosciences, University of Exeter, Exeter, United Kingdom., Singh PK; International Maize and Wheat Improvement Center, (CIMMYT), Texcoco, Mexico., Bentley AR; International Maize and Wheat Improvement Center, (CIMMYT), Texcoco, Mexico., Saunders DGO; John Innes Centre, Norwich Research Park, Norwich, United Kingdom., Tosa Y; Graduate School of Agricultural Science, Kobe University, Kobe, Japan., Croll D; Laboratory of Evolutionary Genetics, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland., Lamour KH; Department of Entomology and Plant Pathology, University of Tennessee, Knoxville, Tennessee, United States of America., Islam T; Institute of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh., Tembo B; Zambia Agricultural Research Institute, Mt. Makulu Central Research Station, Lusaka, Zambia., Win J; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Talbot NJ; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Burbano HA; Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom., Kamoun S; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
Jazyk: angličtina
Zdroj: PLoS biology [PLoS Biol] 2023 Apr 11; Vol. 21 (4), pp. e3002052. Date of Electronic Publication: 2023 Apr 11 (Print Publication: 2023).
DOI: 10.1371/journal.pbio.3002052
Abstrakt: Wheat, one of the most important food crops, is threatened by a blast disease pandemic. Here, we show that a clonal lineage of the wheat blast fungus recently spread to Asia and Africa following two independent introductions from South America. Through a combination of genome analyses and laboratory experiments, we show that the decade-old blast pandemic lineage can be controlled by the Rmg8 disease resistance gene and is sensitive to strobilurin fungicides. However, we also highlight the potential of the pandemic clone to evolve fungicide-insensitive variants and sexually recombine with African lineages. This underscores the urgent need for genomic surveillance to track and mitigate the spread of wheat blast outside of South America and to guide preemptive wheat breeding for blast resistance.
Competing Interests: We have read the journal’s policy and the authors of this manuscript have the following competing interests: KL is a founder of Floodlight Genomics, TI receives funding from Krishi Gobeshona Foundation of Bangladesh, and SK receives funding from industry and has filed patents on plant disease resistance.
(Copyright: © 2023 Latorre et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje