Effect of an Accidental Colchicine Overdose in a COVID-19 Inpatient With Bilateral Pneumonia and Pericardial Effusion.
| Autor: | Mondeshki T; Department of Propaedeutics of Internal Diseases, University Hospital Alexandrovska, Medical University-Sofia, Sofia, BGR., Bilyukov R; Department of Propaedeutics of Internal Diseases, University Hospital Alexandrovska, Medical University-Sofia, Sofia, BGR., Mitev V; Department of Chemistry and Biochemistry, Medical University-Sofia, Sofia, BGR. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Mar 08; Vol. 15 (3), pp. e35909. Date of Electronic Publication: 2023 Mar 08 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.35909 |
| Abstrakt: | A 32-year-old patient with COVID-19 pneumonia and pericardial effusion mistakenly took 15 mg of colchicine over 10 hours. He developed diarrhea that resolved two days after colchicine was stopped. Remarkably, this single overdose of colchicine, without any additional therapy, resulted in the complete recovery of bilateral pneumonia and pericardial effusion, and the patient was discharged on the hospital day 9th. This case demonstrates the possibility that high colchicine doses may have a major role and a dramatic effect in the treatment of COVID-19 patients. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Mondeshki et al.) |
| Databáze: | MEDLINE |
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