Effectiveness of Scalp Cooling to Prevent Chemotherapy-Induced Alopecia in Patients Undergoing Breast Cancer Treatment: A Systematic Review and Meta-analysis.

Autor:	Contreras Molina M; Author Affiliations: Health Research Department, University de Castilla La Mancha (Drs Álvarez Bueno, Cavero Redondo, and Jiménez López), Cuenca; and Servicio de Salud de Castilla-La Mancha (Mr Contreras Molina, Mrs Lucerón Lucas-Torres, and Mrs García Maestro), Albacete, Spain; Universidad Politécnica y Artística del Paraguay (Dr Álvarez Bueno), Asunción; and Facultad de Ciencias de la Salud, Universidad Autónoma de Chile (Dr Cavero Redondo), Talca., Álvarez Bueno C, Cavero Redondo I, Lucerón Lucas-Torres MI, Jiménez López E, García Maestro A
Jazyk:	angličtina
Zdroj:	Cancer nursing [Cancer Nurs] 2024 Jul-Aug 01; Vol. 47 (4), pp. 319-326. Date of Electronic Publication: 2023 Apr 04.
DOI:	10.1097/NCC.0000000000001234
Abstrakt:	Background: Chemotherapy-induced alopecia could cause significant psychological changes, affecting patients' quality of life and their capacity to cope with the disease. Objectives: The aims of this study was to analyze the effectiveness of scalp cooling (SC) to prevent chemotherapy-induced alopecia in patients with breast cancer and to compare the use of automated versus nonautomated therapy delivery devices. Methods: We searched the Cochrane Central Register of Controlled Trials, MEDLINE (through PubMed), Scopus, Web of Science, and ClinicalTrials.gov from their inception to October 2022. A meta-analysis was performed to assess the effects of SC to prevent chemotherapy-induced alopecia in patients with breast cancer using fixed-effects models to calculate the pooled relative risk (RR) and corresponding 95% confidence interval (CI). Results: The 8 included studies showed a 43% reduction in the risk of chemotherapy-induced alopecia (RR, 0.57; 95% CI, 0.50-0.64) after the use of SC. Moreover, the use of automated SC devices showed a 47% reduction (RR, 0.53; 95% CI, 0.45-0.60) in the risk of chemotherapy-induced alopecia versus a 43% reduction in the risk of chemotherapy-induced alopecia for nonautomated SC devices (RR, 0.57; 95% CI, 0.44-0.70). Conclusion: Our results showed that SC significantly reduced the risk of chemotherapy-induced alopecia. Implications for Practice: Local cold application is a nonpharmacologic therapy that may provide a useful intervention to reduce hair loss and contribute to the psychological well-being of women. Scalp cooling contributes directly to reducing concern about altered body image and to reducing anxiety related to self-concept. Competing Interests: The authors have no funding or conflicts of interest to disclose. (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu