Nonsurgical Therapy for Early-Stage Lung Cancer.

Autor:	Daly ME; Department of Radiation Oncology, University of California Davis Comprehensive Cancer Center, 4501 X Street, G-140, Sacramento, CA 95817, USA. Electronic address: medaly@ucdavis.edu., Beagen P; Department of Radiation Oncology, University of California Davis Comprehensive Cancer Center, 4501 X Street, G-140, Sacramento, CA 95817, USA., Madani MH; RadiologyDepartment of Radiology, University of California, Davis, 4860 Y Street, Suite 3100, Sacramento, CA 95817, USA.
Jazyk:	angličtina
Zdroj:	Hematology/oncology clinics of North America [Hematol Oncol Clin North Am] 2023 Jun; Vol. 37 (3), pp. 499-512. Date of Electronic Publication: 2023 Apr 04.
DOI:	10.1016/j.hoc.2023.02.002
Abstrakt:	Treatment options for medically inoperable, early-stage non-small cell lung cancer (NSCLC) include stereotactic ablative radiotherapy (SABR) and percutaneous image guided thermal ablation. SABR is delivered over 1-5 sessions of highly conformal ablative radiation with excellent tumor control. Toxicity is depending on tumor location and anatomy but is typically mild. Studies evaluating SABR in operable NSCLC are ongoing. Thermal ablation can be delivered via radiofrequency, microwave, or cryoablation, with promising results and modest toxicity. We review the data and outcomes for these approaches and discuss ongoing studies. (Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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