The national prevalence of disorders of gut brain interaction in the United Kingdom in comparison to their worldwide prevalence: Results from the Rome foundation global epidemiology study.

Autor: Jaafari H; Leeds Institute of Health Sciences, University of Leeds, Leeds, UK.; Al Qunfudah Health Sciences College, Umm Al-Qura University, Mecca, Saudi Arabia., Houghton LA; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.; Divison of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA., West RM; Leeds Institute of Health Sciences, University of Leeds, Leeds, UK., Agrawal A; Gastroenterology, Doncaster and Bassetlaw Hospitals NHS Trust, Doncaster, UK., Aziz I; Academic Unit of Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust and University of Sheffield, Sheffield, UK., Black CJ; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Corsetti M; NIHR Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust, University of Nottingham, Nottingham, UK.; School of Medicine, Nottingham Digestive Diseases Centre, Nottingham Digestive Diseases Biomedical Research Centre, University of Nottingham, Nottingham, UK., Shuweihdi F; Leeds Institute of Health Sciences, University of Leeds, Leeds, UK., Eugenicos M; Department of Gastroenterology, Western General Hospital, University of Edinburgh, Edinburgh, UK., Paine PA; Northern Care Alliance NHS Foundation Trust, Salford, UK.; Division of Diabetes Endocrinology and Gastroenterology, University of Manchester, Manchester, UK., Ford AC; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Whorwell PJ; Division of Diabetes Endocrinology and Gastroenterology, University of Manchester, Manchester, UK.; Neurogastroenterology Unit, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK., Bangdiwala SI; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Palsson OS; Center for Functional GI & Motility Disorders, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA., Sperber AD; Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Vasant DH; Division of Diabetes Endocrinology and Gastroenterology, University of Manchester, Manchester, UK.; Neurogastroenterology Unit, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Jazyk: angličtina
Zdroj: Neurogastroenterology and motility [Neurogastroenterol Motil] 2023 Jun; Vol. 35 (6), pp. e14574. Date of Electronic Publication: 2023 Apr 05.
DOI: 10.1111/nmo.14574
Abstrakt: Background: There are minimal epidemiological data comparing the burden of disorders of gut brain interaction (DGBI) in the UK with other countries. We compared the prevalence of DGBI in the UK with other countries that participated in the Rome Foundation Global Epidemiology Study (RFGES) online.
Methods: Participants from 26 countries completed the RFGES survey online including the Rome IV diagnostic questionnaire and an in-depth supplemental questionnaire with questions about dietary habits. UK sociodemographic and prevalence data were compared with the other 25 countries pooled together.
Key Results: The proportion of participants with at least one DGBI was lower in UK participants compared with in the other 25 countries (37.6% 95% CI 35.5%-39.7% vs. 41.2%; 95% CI 40.8%-41.6%, p = 0.001). The UK prevalence of 14 of 22 Rome IV DGBI, including irritable bowel syndrome (4.3%) and functional dyspepsia (6.8%), was similar to the other countries. Fecal incontinence, opioid-induced constipation, chronic nausea and vomiting, and cannabinoid hyperemesis (p < 0.05) were more prevalent in the UK. Cyclic vomiting, functional constipation, unspecified functional bowel disorder, and proctalgia fugax (p < 0.05) were more prevalent in the other 25 countries. Diet in the UK population consisted of higher consumption of meat and milk (p < 0.001), and lower consumption of rice, fruit, eggs, tofu, pasta, vegetables/legumes, and fish (p < 0.001).
Conclusions and Inferences: The prevalence and burden of DGBI is consistently high in the UK and in the rest of the world. Opioid prescribing, cultural, dietary, and lifestyle factors may contribute to differences in the prevalence of some DGBI between the UK and other countries.
(© 2023 The Authors. Neurogastroenterology & Motility published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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