The prognostic value of quality of life in atrial fibrillation on patient value.

Autor: Theunissen LJHJ; Máxima Medical Center, Veldhoven, The Netherlands.; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands.; Department of Electrical Engineering (SPS group), Eindhoven University of Technology (TUe), Eindhoven, The Netherlands., van de Pol JAA; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands. Jeroen.v.d.pol@nederlandshartnetwerk.nl.; Department of Electrical Engineering (SPS group), Eindhoven University of Technology (TUe), Eindhoven, The Netherlands. Jeroen.v.d.pol@nederlandshartnetwerk.nl., van Steenbergen GJ; Catharina hospital Eindhoven, Eindhoven, The Netherlands., Cremers HP; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands., van Veghel D; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands.; Catharina hospital Eindhoven, Eindhoven, The Netherlands., van der Voort PH; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands.; Catharina hospital Eindhoven, Eindhoven, The Netherlands., Polak PE; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands.; Anna hospital, Geldrop, The Netherlands., de Jong SFAMS; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands.; Elkerliek hospital, Helmond, The Netherlands., Seelig J; Rijnstate, Arnhem, The Netherlands.; Cardiovascular research institute, Maastricht University, Maastricht, The Netherlands., Smits G; GP Organization POZOB, Veldhoven, The Netherlands., Kemps HMC; Máxima Medical Center, Veldhoven, The Netherlands.; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands.; Department of Industrial Design, Eindhoven University of Technology (TUe), Eindhoven, The Netherlands., Dekker LRC; Netherlands Heart Network, Michelangelolaan 2, Eindhoven, 5623 EJ, The Netherlands.; Catharina hospital Eindhoven, Eindhoven, The Netherlands.; Department of Electrical Engineering (SPS group), Eindhoven University of Technology (TUe), Eindhoven, The Netherlands.
Jazyk: angličtina
Zdroj: Health and quality of life outcomes [Health Qual Life Outcomes] 2023 Apr 05; Vol. 21 (1), pp. 33. Date of Electronic Publication: 2023 Apr 05.
DOI: 10.1186/s12955-023-02112-2
Abstrakt: Background: In this study, the prognostic value of AF-related quality of life (AFEQT) at baseline on Major Adverse Cardiovascular Events (MACE) and improvement of perceived symptoms (EHRA) was assessed. Furthermore, the relationship between QoL and AF-related hospitalizations was assessed.
Methods: A cohort of AF-patients diagnosed between November 2014 and October 2019 in four hospitals embedded within the Netherlands Heart Network were prospectively followed for 12 months. MACE was defined as stroke, myocardial infarction, heart failure and/or mortality. Subsequently, MACE, EHRA score improvement and AF-related hospitalizations between baseline and 12 months of follow-up were recorded.
Results: In total, 970 AF-patients were available for analysis. In analyses with patients with complete information on the confounder subset 36/687 (5.2%) AF-patients developed MACE, 190/432 (44.0%) improved in EHRA score and 189/510(37.1%) were hospitalized during 12 months of follow-up. Patients with a low AFEQT score at baseline more often developed MACE (OR(95%CI): 2.42(1.16-5.06)), more often improved in EHRA score (OR(95%CI): 4.55(2.45-8.44) and were more often hospitalized (OR(95%CI): 4.04(2.22-7.01)) during 12 months post diagnosis, compared to patients with a high AFEQT score at baseline.
Conclusions: AF-patients with a lower quality of life at diagnosis more often develop MACE, more often improve on their symptoms and also were more often hospitalized, compared to AF-patients with a higher quality of life. This study highlights that the integration of patient-reported outcomes, such as quality of life, has the potential to be used as a prognostic indicator of the expected disease course for AF.
(© 2023. The Author(s).)
Databáze: MEDLINE
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