Helicobacter Pylori -Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding.

Autor: Kim SH; Virginia Tech Carilion School of Medicine, Roanoke, VA, USA., Soliman Y; Gastroenterology, City of Hope Phoenix, Goodyear, AZ, USA., Chitnavis VN; Department of Internal Medicine, Division of Gastroenterology, Carilion Clinic and Virginia Tech Carilion School of Medicine, Roanoke, VA, USA., Chitnavis MV; Inflammatory Bowel Disease Section, Atrium Health Gastroenterology, Charlotte, NC, USA.
Jazyk: angličtina
Zdroj: Case reports in gastrointestinal medicine [Case Rep Gastrointest Med] 2023 Mar 23; Vol. 2023, pp. 8244696. Date of Electronic Publication: 2023 Mar 23 (Print Publication: 2023).
DOI: 10.1155/2023/8244696
Abstrakt: Mucosa-associated lymphoid tissue (MALT) lymphoma is a common cause of gastric lymphoma. Although most cases are associated with an H. pylori infection, approximately 10% are H. pylori -negative. Patients with gastric MALT lymphoma are usually asymptomatic or present with nonspecific symptoms such as abdominal pain, dyspepsia, weight loss, and occult gastrointestinal bleeding. In this report, we describe two patients with H. pylori -negative MALT lymphoma who both presented with acute upper gastrointestinal bleeding that led to hemodynamic instability. After resuscitation, emergent endoscopy was performed. Both patients had the t (11; 18) (q21; q21) translocation, which prompted direct treatment by radiotherapy.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2023 Seo Hyun Kim et al.)
Databáze: MEDLINE
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