Adult-Onset IgA Vasculitis Associated With Pulmonary-Renal Syndrome Following COVID-19 Infection: A Case Report and Literature Review.
| Autor: | Alwafi H; Department of Pharmacology and Therapeutics, Umm Al-Qura University, Makkah, SAU., Ashoor D; Department of Medicine and Surgery, Umm Al-Qura University, Makkah, SAU., Dairi M; Department of Internal Medicine, Umm Al-Qura University, Makkah, SAU., Mokhtar G; Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Jeddah, SAU., Dairi K; Department of Internal Medicine, King Faisal Hospital, Makkah, SAU. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Feb 27; Vol. 15 (2), pp. e35527. Date of Electronic Publication: 2023 Feb 27 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.35527 |
| Abstrakt: | Immunoglobulin A (IgA) vasculitis, also known as Henoch-Schönlein purpura (HSP), is an immune complex-mediated inflammation of small blood vessels that leads to tissue destruction with or without organ damage. We described a case of a 41-year-old otherwise healthy female who presented with an ascending rash distributed on both lower extremities and arthralgia. Blood testing revealed high blood urea nitrogen (BUN), creatinine, and inflammatory markers, as well as a negative autoimmune panel. Urinalysis revealed proteinuria and hematuria. A kidney biopsy was performed, which revealed abnormalities. She was started on intravenous (IV) methylprednisolone pulse therapy. Suddenly, she complained of epistaxis and became desaturated. Computed tomography revealed bilateral pleural effusion, and she was transferred to the ICU. Bronchoalveolar lavage was performed and was consistent with an increasing bloodier return. Plasma exchange was performed. The rash and clinical symptoms improved dramatically. This study reports a case of IgA vasculitis based on The European Alliance of Associations for Rheumatology/Pediatric Rheumatology International Trials Organization/Pediatric Rheumatology European Society (EULAR/PRINTO/PRES) criteria associated with pulmonary-renal syndrome following a case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Alwafi et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|