Incidence and predictors of hyperglycemic emergencies among adult diabetic patients in Bahir Dar city public hospitals, Northwest Ethiopia, 2021: A multicenter retrospective follow-up study.

Autor:	Abate MD; Department of Nursing, College of Health Sciences, Woldia University, Woldia, Ethiopia., Semachew A; Department of Adult Health Nursing, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia., Emishaw S; Department of Emergency and Critical Care Nursing, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia., Meseret F; Department of Pediatrics and Child Health Nursing, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia., Azmeraw M; Department of Nursing, College of Health Sciences, Woldia University, Woldia, Ethiopia., Algaw D; Department of Nursing, Bahirdar Health Sciences College, Bahir Dar, Ethiopia., Temesgen D; Department of Nursing, College of Health Sciences, Woldia University, Woldia, Ethiopia., Feleke SF; Department of Public Health, College of Health Sciences, Woldia University, Woldia, Ethiopia., Nuru A; Department of Nursing, College of Medicine and Health Sciences, Wolkite University, Wolkite, Ethiopia., Abate M; Department of Nursing, College of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia., Bantie B; Department of Comprehensive Nursing, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia., Andualem A; Department of Nursing, School of Nursing and Midwifery, Injibara University, Injibara, Ethiopia.
Jazyk:	angličtina
Zdroj:	Frontiers in public health [Front Public Health] 2023 Mar 17; Vol. 11, pp. 1116713. Date of Electronic Publication: 2023 Mar 17 (Print Publication: 2023).
DOI:	10.3389/fpubh.2023.1116713
Abstrakt:	Background: Diabetic ketoacidosis and hyperglycemic hyperosmolar syndrome are the two commonly known life-threatening hyperglycemic emergencies of diabetes mellitus. Despite the growing hyperglycemic emergency impact among adult patients with diabetes, its incidence and predictors have not been well studied in Ethiopia. Thus, this study aimed to assess the incidence and predictors of hyperglycemic emergencies among adult patients with diabetes. Method: A retrospective follow-up study design was conducted among a randomly selected sample of 453 adult patients with diabetes. Data were entered into EPI data version 4.6 and analyzed using STATA version 14.0. A Cox-proportional hazard regression model was fitted to identify the independent predictors of hyperglycemic emergencies, and variables having a p < 0.05 in the multivariable model were considered statistically significant. Result: Among the total adult patients with diabetes included in the study, 147 (32.45%) developed hyperglycemic emergencies. Hence, the overall incidence of hyperglycemic emergencies was 14.6 per 100 person-years observation. The incidence of diabetic ketoacidosis was 12.5 per 100 person-years (35.6 and 6.3 among T1DM and T2DM, respectively). The incidence of the hyperglycemic hyperosmolar syndrome was 2.1 per 100 person-years (0.9 and 2.4 among T1DM and T2DM, respectively). The overall median free survival time was 53.85 months. Type 1 diabetes mellitus [AHR = 2.75, 95% CI (1.68, 4.51)], diabetes duration of ≥ 3 years [AHR = 0.33, 95% CI (0.21, 0.50)], recent acute illness [AHR = 2.99, 95% CI (2.03, 4.43)], presence of comorbidity [AHR = 2.36, 95% CI (1.53, 3.63)], poor glycemic control [AHR = 3.47, 95% CI (2.17, 5.56)], history of medication non-compliance [AHR = 1.85,95% CI (1.24, 2.76)], follow-up frequency of 2-3 months [AHR = 1.79,95% CI (1.06, 3.01)], and without community health insurance [AHR = 1.63, 95% CI (1.14, 2.35)] were significant predictors of hyperglycemic emergencies. Conclusion: The incidence of hyperglycemic emergencies was high. Therefore, giving greater attention to patients with identified predictors could decrease the occurrence of hyperglycemic emergencies and related public health and economic impacts. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Abate, Semachew, Emishaw, Meseret, Azmeraw, Algaw, Temesgen, Feleke, Nuru, Abate, Bantie and Andualem.)
Databáze:	MEDLINE
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