Chloroplast engineering of the green microalgae Chlamydomonas reinhardtii for the production of HAA, the lipid moiety of rhamnolipid biosurfactants.
Autor: | Miró-Vinyals B; Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull (Ramon Llull University), 08017 Barcelona, Spain., Artigues M; Department of Analytical and Applied Chemistry, Institut Químic de Sarrià, Universitat Ramon Llull, 08017 Barcelona, Spain., Wostrikoff K; Sorbonne Université, CNRS, Institut de Biologie Physico-Chimique (Institute of Physico-Chemical Biology), Unité Mixte de Recherche 7141, 75005 Paris, France., Monte E; Centre for Research in Agricultural Genomics (CRAG) CSIC-IRTA-UAB-UB, Campus UAB, Bellaterra, 08193 Barcelona, Spain; Consejo Superior de Investigaciones Científicas (CSIC, Spanish National Research Council), 08028 Barcelona, Spain., Broto-Puig F; Department of Analytical and Applied Chemistry, Institut Químic de Sarrià, Universitat Ramon Llull, 08017 Barcelona, Spain., Leivar P; Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull (Ramon Llull University), 08017 Barcelona, Spain. Electronic address: pablo.leivar@iqs.url.edu., Planas A; Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull (Ramon Llull University), 08017 Barcelona, Spain; Royal Academy of Sciences and Arts of Barcelona, Chemistry section, Barcelona, Spain. Electronic address: antoni.planas@iqs.url.edu. |
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Jazyk: | angličtina |
Zdroj: | New biotechnology [N Biotechnol] 2023 Sep 25; Vol. 76, pp. 1-12. Date of Electronic Publication: 2023 Mar 31. |
DOI: | 10.1016/j.nbt.2023.03.005 |
Abstrakt: | Hydroxyalkanoyloxyalkanoates (HAA) are lipidic surfactants with a number of potential applications, but more remarkably, they are the biosynthetic precursors of rhamnolipids (RL), which are preferred biosurfactants thanks to their excellent physicochemical properties, biological activities, and environmental biodegradability. Because the natural highest producer of RLs is the pathogenic bacterium Pseudomonas aeruginosa, important efforts have been dedicated to transfer production to heterologous non-pathogenic microorganisms. Unicellular photosynthetic microalgae are emerging as important hosts for sustainable industrial biotechnology due to their ability to transform CO Competing Interests: Declaration of Competing Interest The authors declare that they have no competing interests. (Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.) |
Databáze: | MEDLINE |
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