Little brain, little minds: The big role of the cerebellum in social development.

Autor:	Olson IR; Department of Psychology and Neuroscience, Temple University, Philadephia PA, USA. Electronic address: iolson@temple.edu., Hoffman LJ; Department of Psychology and Neuroscience, Temple University, Philadephia PA, USA., Jobson KR; Department of Psychology and Neuroscience, Temple University, Philadephia PA, USA., Popal HS; Department of Psychology and Neuroscience, Temple University, Philadephia PA, USA., Wang Y; State Key Laboratory of Cognitive Neuroscience and Learning, and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Jazyk:	angličtina
Zdroj:	Developmental cognitive neuroscience [Dev Cogn Neurosci] 2023 Apr; Vol. 60, pp. 101238. Date of Electronic Publication: 2023 Mar 27.
DOI:	10.1016/j.dcn.2023.101238
Abstrakt:	Seminal work in the 1990's found alterations in the cerebellum of individuals with social disorders including autism spectrum disorder and schizophrenia. In neurotypical populations, distinct portions of the posterior cerebellum are consistently activated in fMRI studies of social cognition and it has been hypothesized that the cerebellum plays an essential role in social cognition, particularly in theory of mind. Here we review the lesion literature and find that the effect of cerebellar damage on social cognition is strongly linked to the age of insult, with dramatic impairments observed after prenatal insult, strong deficits observed after childhood damage, and mild and inconsistent deficits observed following damage to the adult cerebellum. To explain the developmental gradient, we propose that early in life, the forward model dominates cerebellar computations. The forward model learns and uses errors to help build schemas of our interpersonal worlds. Subsequently, we argue that once these schemas have been built up, the inverse model, which is the foundation of automatic processing, becomes dominant. We provide suggestions for how to test this, and also outline directions for future research. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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