Ethical Considerations of Genome Sequencing for Pediatric Patients.

Autor: Sergi MM; From theUniversity Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH; Case Western Reserve University School of Medicine, Cleveland, OH; University Hospitals Cleveland Medical Center, Cleveland, OH; MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, IL. Electronic address: michelle.sergi2@uhhospitals.org., Keinath MC; Case Western Reserve University School of Medicine, Cleveland, OH; University Hospitals Cleveland Medical Center, Cleveland, OH., Fanaroff J; From theUniversity Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH; Case Western Reserve University School of Medicine, Cleveland, OH., Miller KE; From theUniversity Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH.
Jazyk: angličtina
Zdroj: Seminars in pediatric neurology [Semin Pediatr Neurol] 2023 Apr; Vol. 45, pp. 101039. Date of Electronic Publication: 2023 Mar 01.
DOI: 10.1016/j.spen.2023.101039
Abstrakt: Advancements in genetic testing in the healthcare setting, most recently genomic sequencing, has enhanced our ability to diagnose genetic conditions. These advances include increased accessibility and affordability of genomic technologies. With expanded use comes the potential for significant ethical challenges for clinicians, particularly considering the implications of testing a child for one condition and incidentally finding a different condition or health risk. In this focused review, we address various ethical considerations from informed consent to the rights of a child undergoing genetic testing.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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