S1 represents multisensory contexts and somatotopic locations within and outside the bounds of the cortical homunculus.

Autor:	Rosenthal IA; Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; T&C Chen Brain-machine Interface Center, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: rosenthalia@caltech.edu., Bashford L; Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; T&C Chen Brain-machine Interface Center, California Institute of Technology, Pasadena, CA 91125, USA., Kellis S; Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; T&C Chen Brain-machine Interface Center, California Institute of Technology, Pasadena, CA 91125, USA; Department of Neurological Surgery, Keck School of Medicine of USC, Los Angeles, CA 90033, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA 90033, USA., Pejsa K; Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; T&C Chen Brain-machine Interface Center, California Institute of Technology, Pasadena, CA 91125, USA., Lee B; Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Department of Neurological Surgery, Keck School of Medicine of USC, Los Angeles, CA 90033, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA 90033, USA., Liu C; Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Department of Neurological Surgery, Keck School of Medicine of USC, Los Angeles, CA 90033, USA; USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, CA 90033, USA; Rancho Los Amigos National Rehabilitation Center, Downey, CA 90242, USA., Andersen RA; Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; T&C Chen Brain-machine Interface Center, California Institute of Technology, Pasadena, CA 91125, USA.
Jazyk:	angličtina
Zdroj:	Cell reports [Cell Rep] 2023 Apr 25; Vol. 42 (4), pp. 112312. Date of Electronic Publication: 2023 Mar 30.
DOI:	10.1016/j.celrep.2023.112312
Abstrakt:	Recent literature suggests that tactile events are represented in the primary somatosensory cortex (S1) beyond its long-established topography; in addition, the extent to which S1 is modulated by vision remains unclear. To better characterize S1, human electrophysiological data were recorded during touches to the forearm or finger. Conditions included visually observed physical touches, physical touches without vision, and visual touches without physical contact. Two major findings emerge from this dataset. First, vision strongly modulates S1 area 1, but only if there is a physical element to the touch, suggesting that passive touch observation is insufficient to elicit neural responses. Second, despite recording in a putative arm area of S1, neural activity represents both arm and finger stimuli during physical touches. Arm touches are encoded more strongly and specifically, supporting the idea that S1 encodes tactile events primarily through its topographic organization but also more generally, encompassing other areas of the body. Competing Interests: Declaration of interests The authors declare no competing interests. (Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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