Interdisciplinarity in HIV prevention research: the experience of the PrEP1519 study protocol among adolescent MSM and TGW in Brazil.

Autor: Dourado I; Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brasil., Magno L; Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brasil.; Departamento de Ciências da Vida, Universidade do Estado da Bahia, Salvador, Brasil., Greco DB; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil., Zucchi EM; Universidade Católica de Santos, Santos, Brasil., Ferraz D; Escola Fiocruz de Governo, Fiocruz Brasília, Brasília, Brasil.; Radiations: Défense, Santé, Environnement, Université Lumière Lyon 2, Lyon, France., Westin MR; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil., Grangeiro A; Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil.
Jazyk: angličtina
Zdroj: Cadernos de saude publica [Cad Saude Publica] 2023 Mar 27; Vol. 39Suppl 1 (Suppl 1), pp. e00143221. Date of Electronic Publication: 2023 Mar 27 (Print Publication: 2023).
DOI: 10.1590/0102-311XEN143221
Abstrakt: At the end of 2017, Brazil adopted HIV pre-exposure prophylaxis (PrEP) as part of a combination prevention strategy for the most at-risk populations. However, Brazil does not have specific guidelines for PrEP use among adolescents aged < 18 years. Therefore, researchers from different health disciplines conducted PrEP1519, the first PrEP demonstration cohort study, ongoing in three Brazilian cities - Salvador, Belo Horizonte, and São Paulo - among adolescent men who have sex with men and transgender women, aged 15-19 years. This study aims to evaluate the effectiveness of PrEP in real-world settings. Quantitative and qualitative methods were integrated to obtain data on PrEP acceptability, uptake, use, and adherence. Moreover, comprehensive services and friendly environments were implemented in the PrEP1519 clinics. This study aims to describe the collaborative efforts of interdisciplinary practices in the development of the PrEP1519 study. The articulation of researchers from different institutions and areas is challenging; but it also allows for a broader outlook on questions regarding the direction of the research, while enriching the decisions needed to be taken during the interactions and negotiations among the different individuals, including the youth team and participants. Furthermore, it reflects on the communication process between cultures and languages considering the trans-epistemic arena of knowledge production about HIV, sexually transmitted infections, PrEP, and other combination prevention strategies for adolescents.
Databáze: MEDLINE