Viral co-infection with human respiratory syncytial virus in suspected acute and severe respiratory tract infections during COVID-19 pandemic in Yaoundé, Cameroon, 2020-2021.

Autor: Moumbeket Yifomnjou MH; Centre Pasteur of Cameroon, Yaounde, Cameroon.; Laboratory of Microbiology, University of Yaounde I, Yaounde, Cameroon., Monamele GC; Centre Pasteur of Cameroon, Yaounde, Cameroon., Njankouo-Ripa M; Centre Pasteur of Cameroon, Yaounde, Cameroon., Fatawou Modiyinji A; Centre Pasteur of Cameroon, Yaounde, Cameroon., Ngoupo PA; Centre Pasteur of Cameroon, Yaounde, Cameroon., Boyomo O; Laboratory of Microbiology, University of Yaounde I, Yaounde, Cameroon., Njouom R; Centre Pasteur of Cameroon, Yaounde, Cameroon.
Jazyk: angličtina
Zdroj: Influenza and other respiratory viruses [Influenza Other Respir Viruses] 2023 Mar; Vol. 17 (3), pp. e13131.
DOI: 10.1111/irv.13131
Abstrakt: Background: Acute lower respiratory tract infections (ALRIs) are one one of the leading causes of morbidity and mortality among people of all ages worldwide, particularly in low- and middle-income countries (LMICs). The purpose of this study was to determine epidemiological characteristics of respiratory viruses in acute respiratory infection (ARI) patients during the COVID-19 pandemic in Yaoundé, Cameroon.
Methods: Patients were monitored for respiratory symptoms as part of the surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viral infections. Patients of all ages with respiratory symptoms less than 5 days were considered. Sociodemographic and clinical data as well as nasopharyngeal samples was collected from patients. Nasopharyngeal samples were tested for SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) using real-time reverse-transcription polymerase chain reaction methods. Virus distribution and demographic data were analyzed with R version 2.15.1.
Results: From July 2020 to October 2021, 1120 patients were included. The overall viral detection rate was 32.5%, including 9.5% for RSV, 12.6% for influenza virus and 12.8% for SARS-CoV-2. Co-infections were detected in 6.9% of positive cases. While RSV and influenza virus showed seasonal trends, SARS-CoV-2 was detected throughout the study period.
Conclusion: We found that during COVID-19 pandemic, respiratory viruses play an important role in etiology of influenza-like illness in Cameroon, and this observation was true for patients of all ages.
(© 2023 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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