| Autor: |
Nguyen TTH; College of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi 100000, Vietnam.; Faculty of Animal Science and Veterinary Medicine, Bac Giang Agriculture and Forestry University, Bac Giang 230000, Vietnam., Nguyen VT; Institute of Veterinary Science and Technology (IVST), Hanoi 100000, Vietnam., Le PN; Institute of Veterinary Science and Technology (IVST), Hanoi 100000, Vietnam., Mai NTA; Institute of Veterinary Science and Technology (IVST), Hanoi 100000, Vietnam., Dong VH; College of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi 100000, Vietnam., Bui TAD; College of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi 100000, Vietnam., Nguyen TL; College of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi 100000, Vietnam., Ambagala A; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB R3E 3M4, Canada., Le VP; College of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi 100000, Vietnam.; Institute of Veterinary Science and Technology (IVST), Hanoi 100000, Vietnam. |
| Abstrakt: |
African swine fever (ASF) is currently Vietnam's most economically significant swine disease. The first ASF outbreak in Vietnam was reported in February 2019. In this study, VNUA/HY/ASF1 strain isolated from the first ASF outbreak was used to infect 10 eight-week-old pigs orally with 10 3 HAD 50 per animal. The pigs were observed daily for clinical signs, and whole blood samples were collected from each animal for viremia detection. Dead pigs were subjected to full post-mortem analyses. All 10 pigs displayed acute or subacute clinical signs and succumbed to the infection between 10 to 27 (19.8 ± 4.66) days post-inoculation (dpi). The onset of clinical signs started around 4-14 dpi. Viremia was observed in pigs from 6-16 dpi (11.2 ± 3.55). Enlarged, hyperemic, and hemorrhagic lymph nodes, enlarged spleen, pneumonia, and hydropericardium were observed at post-mortem examinations. |
