Chemical Evaluation, Phytotoxic Potential, and In Silico Study of Essential Oils from Leaves of Guatteria schomburgkiana Mart. and Xylopia frutescens Aubl. (Annonaceae) from the Brazilian Amazon.

Autor: de Moraes ÂAB; Faculdade de Engenharia Química, Instituto de Tecnologia, Universidade Federal do Pará, Rua Augusto Corrêa, 01, Guamá, Belem 66075-900, PA, Brazil.; Laboratório Adolpho Ducke, Coordenação de Botânica, Museu Paraense Emílio Goeldi, Av. Perimetral, 1901, Terra Firme, Belem 66077-830, PA, Brazil., Cascaes MM; Laboratório Adolpho Ducke, Coordenação de Botânica, Museu Paraense Emílio Goeldi, Av. Perimetral, 1901, Terra Firme, Belem 66077-830, PA, Brazil.; Programa de Pós-Graduação em Química, Universidade Federal do Pará, Rua Augusto Corrêa, 01, Guamá, Belem 66075-900, PA, Brazil., do Nascimento LD; Laboratório Adolpho Ducke, Coordenação de Botânica, Museu Paraense Emílio Goeldi, Av. Perimetral, 1901, Terra Firme, Belem 66077-830, PA, Brazil., de Jesus Pereira Franco C; Laboratório Adolpho Ducke, Coordenação de Botânica, Museu Paraense Emílio Goeldi, Av. Perimetral, 1901, Terra Firme, Belem 66077-830, PA, Brazil., Ferreira OO; Laboratório Adolpho Ducke, Coordenação de Botânica, Museu Paraense Emílio Goeldi, Av. Perimetral, 1901, Terra Firme, Belem 66077-830, PA, Brazil.; Programa de Pós-Graduação em Biotecnologia e Biodiversidade-Rede BIONORTE, Universidade Federal do Pará, Rua Augusto Corrêa, 01, Guamá, Belem 66075-900, PA, Brazil., Anjos TOD; Programa de Pós-Graduação em Botânica Tropical, Universidade Federal Rural da Amazônia, Avenida Tancredo Neves, 2501, Belem 66077-830, PA, Brazil., Karakoti H; Department of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar 263145, Uttarakhand, India., Kumar R; Department of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar 263145, Uttarakhand, India., da Silva Souza-Filho AP; Embrapa Amazônia Oriental, Av. Dr. Enéas Pinheiro, Marco, Belem 66095-903, PA, Brazil., de Oliveira MS; Faculdade de Engenharia Química, Instituto de Tecnologia, Universidade Federal do Pará, Rua Augusto Corrêa, 01, Guamá, Belem 66075-900, PA, Brazil.; Programa de Pós-Graduação em Biotecnologia e Biodiversidade-Rede BIONORTE, Universidade Federal do Pará, Rua Augusto Corrêa, 01, Guamá, Belem 66075-900, PA, Brazil., de Aguiar Andrade EH; Faculdade de Engenharia Química, Instituto de Tecnologia, Universidade Federal do Pará, Rua Augusto Corrêa, 01, Guamá, Belem 66075-900, PA, Brazil.; Laboratório Adolpho Ducke, Coordenação de Botânica, Museu Paraense Emílio Goeldi, Av. Perimetral, 1901, Terra Firme, Belem 66077-830, PA, Brazil.; Programa de Pós-Graduação em Biotecnologia e Biodiversidade-Rede BIONORTE, Universidade Federal do Pará, Rua Augusto Corrêa, 01, Guamá, Belem 66075-900, PA, Brazil.
Jazyk: angličtina
Zdroj: Molecules (Basel, Switzerland) [Molecules] 2023 Mar 14; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 14.
DOI: 10.3390/molecules28062633
Abstrakt: The essential oils (EOs) of Guatteria schomburgkiana (Gsch) and Xylopia frutescens (Xfru) (Annonaceae) were obtained by hydrodistillation, and their chemical composition was evaluated by gas chromatography-mass spectrometry (GC/MS). Herbicide activity was measured by analyzing the seed germination percentage and root and hypocotyl elongation of two invasive species: Mimosa pudica and Senna obtusifolia . The highest yield was obtained for the EO of Xfru (1.06%). The chemical composition of Gsch was characterized by the presence of the oxygenated sesquiterpenes spathulenol (22.40%) and caryophyllene oxide (14.70%). Regarding the EO of Xfru, the hydrocarbon monoterpenes α-pinene (35.73%) and β-pinene (18.90%) were the components identified with the highest concentrations. The germination of seeds of S . obtusifolia (13.33 ± 5.77%) showed higher resistance than that of seeds of M . pudica (86.67 ± 5.77%). S. obtusifolia was also more sensitive to the EO of Xfru in terms of radicle (55.22 ± 2.72%) and hypocotyl (71.12 ± 3.80%) elongation, while M . pudica showed greater sensitivity to the EO of Gsch. To screen the herbicidal activity, the molecular docking study of the major and potent compounds was performed against 4-hydroxyphenylpyruvate dioxygenase (HPPD) protein. Results showed good binding affinities and attributed the strongest inhibitory activity to δ-cadinene for the target protein. This work contributes to the study of the herbicidal properties of the EOs of species of Annonaceae from the Amazon region.
Databáze: MEDLINE
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