Habitual physical activity in patients born with oesophageal atresia: a multicenter cross-sectional study and comparison to a healthy reference cohort matched for gender and age.

Autor: König TT; Department of Pediatric Surgery, Universitätsmedizin, Johannes Gutenberg-University Mainz, Langenbeckstr. 1, Mainz, 55131, Germany. Tatjana.Koenig@unimedizin-mainz.de., Frankenbach ML; Department of Pediatric Surgery, Universitätsmedizin, Johannes Gutenberg-University Mainz, Langenbeckstr. 1, Mainz, 55131, Germany., Gianicolo E; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), Universitätsmedizin, Johannes Gutenberg-University Mainz, Mainz, Germany.; Institute of Clinical Physiology, National Research Council, Lecce, Italy., Holler AS; Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany., von Sochaczewski CO; Sektion Kinderchirurgie, Klinik und Poliklinik Für Allgemein-, Viszeral-, Thorax- Und Gefäßchirurgie, Universitätsklinikum Bonn, Bonn, Germany., Wessel L; Pediatric Surgery, University Medical Centre Mannheim, Mannheim, Germany., Widenmann A; Patient Organisation for Esophageal Diseases KEKS e.V., Stuttgart, Germany., Klos L; Institute of Sports and Sports Science (IfSS), Karlsruhe Institute of Technology, Karlsruhe, Germany., Kolb S; Institute of Sports and Sports Science (IfSS), Karlsruhe Institute of Technology, Karlsruhe, Germany., Siaplaouras J; University of Applied Sciences Fulda, Health Sciences, Fulda, Germany., Niessner C; Institute of Sports and Sports Science (IfSS), Karlsruhe Institute of Technology, Karlsruhe, Germany.
Jazyk: angličtina
Zdroj: European journal of pediatrics [Eur J Pediatr] 2023 Jun; Vol. 182 (6), pp. 2655-2663. Date of Electronic Publication: 2023 Mar 28.
DOI: 10.1007/s00431-023-04923-3
Abstrakt: Oesophageal atresia (EA) is associated with life-long gastrointestinal and respiratory morbidity and other associated malformations. The aim of this study is to compare physical activity (PA) levels of children and adolescents with and without EA. A validated questionnaire (MoMo-PAQ) was used to evaluate PA in EA patients EA (4-17 years), who were randomly matched for gender and age (1:5) with a representative sample of the Motorik-Modul Longitudinal Study (n = 6233). Sports activity per week (sports index) and minutes of moderate to vigorous physical activity per week (MVPA minutes) were calculated. Correlations between PA and medical factors were analysed. In total, 104 patients and 520 controls were included. Children with EA were significantly less active at higher intensities (mean MPVA minutes 462; 95% confidence interval (CI): 370-554) compared to controls (626; 95% CI: 576-676), although there was no statistically significant difference in the sports index (187; 95% CI: 156-220 versus 220; 95% CI: 203-237). A lower mean weight-for-age and height-for-age, additional urogenital (r =  - 0.20, p = 0.04) or anorectal malformation (r =  - 0.24, p = 0.01) were associated with fewer MVPA minutes. For other medical factors (prematurity, type of repair, congenital heart disease, skeletal malformation or symptom load), no statistically significant association with PA was found.  Conclusion: EA patients participated in PA at a similar level but lower intensities compared to the reference cohort. PA in EA patients was largely independent of medical factors.
Trial Registration: German Clinical Trials Register (ID: DRKS00025276) on September 6, 2021.
What Is Known: • Oesophageal atresia is associated with a low body weight and height, delayed development of motor skills and impaired lung function and exercise capacity.
What Is New: • Patients with oesophageal atresia have a similar amount of sports activity per week but engage significantly less in moderate to vigorous physical activities compared to peers. • Physical activity was  associated with weight-for-age and height-for-age, but largely independent of symptom load and other medical factors.
(© 2023. The Author(s).)
Databáze: MEDLINE
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