Effect of Race and Ethnicity on Pulmonary Function Testing Interpretation: An American College of Chest Physicians (CHEST), American Association for Respiratory Care (AARC), American Thoracic Society (ATS), and Canadian Thoracic Society (CTS) Evidence Review and Research Statement.

Autor: Marciniuk DD; Division of Respirology, Critical Care and Sleep Medicine, Respiratory Research Center, University of Saskatchewan, Saskatoon, SK. Electronic address: Darcy.marciniuk@usask.ca., Becker EA; Division of Respiratory Care, Department of Cardiopulmonary Sciences Rush University, Chicago, IL., Kaminsky DA; Pulmonary and Critical Care, University of Vermont Larner College of Medicine, Burlington, VT., McCormack MC; Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD., Stanojevic S; Department of Community Health and Epidemiology, Dalhousie University, Halifax, NS., Bhakta NR; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA., Bime C; University of Arizona College of Medicine, Tucson, AZ., Comondore V; Division of Respirology, McMaster University, Hamilton, ON; Division of Respirology, William Osler Health System, Brampton, ON., Cowl CT; Division of Public Health, Infectious Diseases and Occupational Medicine and the Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN., Dell S; Department of Pediatrics and BC Children's Research Institute, University of British Columbia, Vancouver, BC, Canada., Haynes J; Pulmonary Function Laboratory, Elliot Health System, Manchester, NH., Jaffe F; Temple University Hospital, Philadelphia, PA., Mottram C; PFW Consulting LLC, Hayfield, MN., Sederstrom N; Health Equity Department, Hennepin Healthcare, Minneapolis, MN., Townsend M; M.C. Townsend Associates, LLC, Pittsburgh, PA; University of Pittsburgh School of Public Health, Pittsburgh, PA., Iaccarino JM; American College of Chest Physicians, Chicago, IL; Chobanian and Avedisian School of Medicine, Boston University, Boston, MA.
Jazyk: angličtina
Zdroj: Chest [Chest] 2023 Aug; Vol. 164 (2), pp. 461-475. Date of Electronic Publication: 2023 Mar 25.
DOI: 10.1016/j.chest.2023.03.026
Abstrakt: Background: Calls have been made to discontinue the routine use of race and ethnicity in medicine. Specific to respiratory medicine, the use of race- and ethnicity-specific reference equations for the interpretation of pulmonary function test (PFT) results has been questioned.
Research Questions: Three key questions were addressed: (1) What is the current evidence supporting the use of race- and ethnicity-specific reference equations for the interpretation of PFTs? (2) What are the potential clinical implications of the use or nonuse of race and ethnicity in interpreting PFT results? and (3) What research gaps and questions must be addressed and answered to understand better the effect of race and ethnicity on PFT results interpretation and potential clinical and occupational health implications?
Study Design and Methods: A joint multisociety (American College of Chest Physicians, American Association for Respiratory Care, American Thoracic Society, and Canadian Thoracic Society) expert panel was formed to undertake a comprehensive evidence review and to develop a statement with recommendations to address the research questions.
Results: Several assumptions and gaps, both in the published literature and in our evolving understanding of lung health, were identified. It seems that many past perceptions and practices regarding the effect of race and ethnicity on PFT results interpretation are based on limited scientific evidence and measures that lack reliability.
Interpretation: A need exists for more and better research that will inform our field about these many uncertainties and will serve as a foundation for future recommendations in this area. The identified shortcomings should not be discounted or dismissed because they may enable flawed conclusions, unintended consequences, or both. Addressing the identified research gaps and needs would allow a better-a more informed-understanding of the effects of race and ethnicity on PFT results interpretation.
(Copyright © 2023 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE