[From the forest to the ICU and back: an investigative work-up of Amanita phalloides poisoning].

Autor:	Murad M; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Anslinger TM; Medizinische Klinik II, Universitätsklinikum RWTH Aachen, Aachen, Germany.; Institut für Experimentelle Innere Medizin und Systembiologie, RWTH Aachen, Aachen, Germany., Frank D; Pilzsachverständiger der Deutschen Gesellschaft für Mykologie (DGfM) e.V., Feuerwehr Much, Much, Germany., Hohlstein P; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., van den Burg L; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Brozat JF; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Pollmanns MR; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Fromme M; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Grünert M; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Lubberich R; Medizinische Klinik I, Universitätsklinikum RWTH Aachen, Aachen, Germany., Wirtz TH; Medizinische Klinik III, Universtitätsklinikum RWTH Aachen, Aachen, Germany., Hamesch K; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Trautwein C; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Abu Jhaisha S; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany., Koch A; Medizinische Klinik III, Universitätsklinikum RWTH Aachen, Aachen, Germany.
Jazyk:	němčina
Zdroj:	Zeitschrift fur Gastroenterologie [Z Gastroenterol] 2024 Feb; Vol. 62 (2), pp. 204-207. Date of Electronic Publication: 2023 Mar 27.
DOI:	10.1055/a-2028-7630
Abstrakt:	With over 90% of deaths following mushroom ingestion, poisoning with Amatoxin is one of the most dangerous food intoxications. Despite numerous case reports, treatment recommendations are based on a moderate level of evidence due to a lack of randomized controlled trials.We present the case of a 32-year-old patient who presented with acute liver failure after Amanita phalloides (green death cap mushroom) ingestion and whose therapeutic success was significantly influenced by the administration of activated charcoal, silibinin, and N-acetylcysteine as well as the determined research of an external mycologist.In various retrospective studies, a relevant reduction of mortality could be shown by the mentioned medicinal measures. Despite the high estimated amount of ingestion, we could confirm the effectiveness of this combination therapy in this case.Here, in addition to the drug therapy, attention should also be paid to the extraordinary cooperation of a mycologist, who was able to confirm the suspected diagnosis by his investigative approach and thus contributed to the success of the therapy. Immediate contact with the competent poison centre and the involvement of an expert is therefore recommended in unclear situations. Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht. (Thieme. All rights reserved.)
Databáze:	MEDLINE
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