Association between mobility, non-pharmaceutical interventions, and COVID-19 transmission in Ghana: A modelling study using mobile phone data.

Autor:	Gibbs H; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom., Liu Y; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom., Abbott S; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom., Baffoe-Nyarko I; Ghana Health Service, Ministry of Health, Accra, Ghana., Laryea DO; Ghana Health Service, Ministry of Health, Accra, Ghana., Akyereko E; Ghana Health Service, Ministry of Health, Accra, Ghana., Kuma-Aboagye P; Ghana Health Service, Ministry of Health, Accra, Ghana., Asante IA; Noguchi Memorial Institute for Medical Research, Accra, Ghana., Mitjà O; Fight AIDS and Infectious Diseases Foundation, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Ampofo W; Noguchi Memorial Institute for Medical Research, Accra, Ghana., Asiedu-Bekoe F; Ghana Health Service, Ministry of Health, Accra, Ghana., Marks M; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom.; Hospital for Tropical Diseases, University College London Hospital, London, United Kingdom.; Division of Infection and Immunity, University College London, London, United Kingdom., Eggo RM; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Jazyk:	angličtina
Zdroj:	PLOS global public health [PLOS Glob Public Health] 2022 Sep 13; Vol. 2 (9), pp. e0000502. Date of Electronic Publication: 2022 Sep 13 (Print Publication: 2022).
DOI:	10.1371/journal.pgph.0000502
Abstrakt:	Governments around the world have implemented non-pharmaceutical interventions to limit the transmission of COVID-19. Here we assess if increasing NPI stringency was associated with a reduction in COVID-19 cases in Ghana. While lockdowns and physical distancing have proven effective for reducing COVID-19 transmission, there is still limited understanding of how NPI measures are reflected in indicators of human mobility. Further, there is a lack of understanding about how findings from high-income settings correspond to low and middle-income contexts. In this study, we assess the relationship between indicators of human mobility, NPIs, and estimates of Rt, a real-time measure of the intensity of COVID-19 transmission. We construct a multilevel generalised linear mixed model, combining local disease surveillance data from subnational districts of Ghana with the timing of NPIs and indicators of human mobility from Google and Vodafone Ghana. We observe a relationship between reductions in human mobility and decreases in Rt during the early stages of the COVID-19 epidemic in Ghana. We find that the strength of this relationship varies through time, decreasing after the most stringent period of interventions in the early epidemic. Our findings demonstrate how the association of NPI and mobility indicators with COVID-19 transmission may vary through time. Further, we demonstrate the utility of combining local disease surveillance data with large scale human mobility data to augment existing surveillance capacity to monitor the impact of NPI policies. Competing Interests: The authors declare no competing interests. (Copyright: © 2022 Gibbs et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze:	MEDLINE
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