The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment.

Autor:	Shrestha Y; Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B. G. Nagara, India., Shivalingegowda RK; Department of Otorhinolaryngology and Head & Neck Surgery, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, B. G. Nagara, India., Avinash MJ; Department of General Surgery, Sapthagiri Institute of Medical Sciences and Research Centre, Bangalore, India., Kenchegowda SBH; Department of Orthopaedics, Jayanagar General Hospital, Bangalore, India., Moktan JB; Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B. G. Nagara, India., Doddasamiah SM; Department of General Surgery, Sapthagiri Institute of Medical Sciences and Research Centre, Bangalore, India., Tambat RM; Department of General Surgery, Sapthagiri Institute of Medical Sciences and Research Centre, Bangalore, India., Golshetty DG; Department of Paediatrics, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, B. G. Nagara, India., Ganesh VS; Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B. G. Nagara, India., Venkataraman R; Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B. G. Nagara, India.
Jazyk:	angličtina
Zdroj:	PLOS global public health [PLOS Glob Public Health] 2022 Jul 13; Vol. 2 (7), pp. e0000641. Date of Electronic Publication: 2022 Jul 13 (Print Publication: 2022).
DOI:	10.1371/journal.pgph.0000641
Abstrakt:	A saturated health care system with a lack of evidence-based antiviral medicine and ignorance of antimicrobial stewardship during pandemics has prompted clinicians to prescribe a broad-spectrum antibiotic more often. A prospective, cross-sectional study of COVID-infected patients was conducted to gain insight into antibiotic prescribing practices and their impact on antimicrobial resistance. The antibiotic susceptibility test was performed using the disc diffusion method. 318 patients met the study's inclusion criteria, with a mean age of 46 years and 55% (175) of them being males. Antibiotics were prescribed for 93.72% (209) of mild cases, 92.45% (49) of moderate cases, 96.15% (25) of severe cases, and 100% (16) of critical cases of COVID-19. A total of 95 samples were sent in for culture and antibiotic sensitivity testing, with 58.95% (56) confirming growth. The majority of the growth was found to contain E. coli (14). In 54.9% of cases, antibiotics with less than 50% sensitivity to curing bacterial infection were detected. In the study, we found that antibiotics were being used unnecessarily in excessive quantities and that more than half of the antibiotics were less sensitive to isolated bacteria. Competing Interests: The authors have declared that no competing interests exist. (Copyright: © 2022 Shrestha et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze:	MEDLINE
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