Mitigation behavior prior to COVID-19 vaccination availability is associated with COVID-19 infection and time to vaccination.

Autor: Neighbors CE; Hubert-Yeargan Center for Global Health, Duke University, Durham, North Carolina, United States of America., Sloane R; Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, United States of America., Pieper CF; Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, United States of America., Wixted D; Duke Clinical and Translational Science Institute, Duke University, Durham, North Carolina, United States of America., Woods CW; Hubert-Yeargan Center for Global Health, Duke University, Durham, North Carolina, United States of America.; Departments of Medicine and Pathology, Duke University Medical Center, Durham, North Carolina, United States of America., Newby LK; Duke Clinical and Translational Science Institute, Duke University, Durham, North Carolina, United States of America.; Duke Clinical Research Institute, Duke University, Durham, North Carolina, United States of America.; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2023 Mar 24; Vol. 18 (3), pp. e0283381. Date of Electronic Publication: 2023 Mar 24 (Print Publication: 2023).
DOI: 10.1371/journal.pone.0283381
Abstrakt: Background: Mitigation behaviors reduce the incidence of COVID-19 infection. Determining characteristics of groups defined by mitigation behaviors compliance may be useful to inform targeted public health policies and interventions. This study aimed to identify groups of individuals according to self-reported compliance with COVID-19 mitigation behaviors, define compliance class characteristics, and explore associations between compliance classes and important study and public health outcomes.
Methods and Findings: We studied 1,410 participants in the Cabarrus County COVID-19 Prevalence and Immunity longitudinal cohort study (June 2020 to December 2021) who were asked 10 questions regarding compliance with recommended COVID-19 mitigation behaviors. By Latent Class Analysis, 1,381 participants were categorized into 3 classes (most [49.4%], moderately [45.0%], and least [5.6%] compliant). Compared with the most compliant class, the least and moderately compliant classes were younger (mean = 61.9 v. 59.0 v. 53.8 years), had fewer medical conditions per individual (1.37 v. 1.08 v. 0.77), and differed in Hispanic ethnicity (6.2% v. 2.8% v. 9.1%) and COVID-19 vaccine intention (65.8% v. 59.8% v. 35.1%). Compared to the most compliant class, the least compliant class had fewer women (54.6% v. 76.3%), fewer insured individuals (92.2% v. 97.4%), and more withdrew from study participation early (28.6% v. 16.0%). Relative to the most compliant class, the least compliant class had a higher likelihood of COVID-19 infection (OR = 2.08 [95% CI 1.13, 3.85]), lower rate of COVID-19 vaccination (72.6% v. 95.1%), and longer time to 50% COVID-19 vaccination following eligibility (8-9 vs 16 days).
Conclusions: Classes defined by mitigation behaviors compliance had distinct characteristics, including age, sex, medical history, and ethnicity, and were associated with important study and public health outcomes. Targeted public health policies and interventions according to the compliance group characteristics may be of value in current and future pandemic responses to increase compliance.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2023 Neighbors et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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