THE MICROBIOLOGICAL STRUCTURE OF OTOMYCOSIS: SENSITIVITY PROFILE OF AGENTS TO ANTIFUNGAL DRUGS.
Autor: | Smiianov VA; SUMY STATE UNIVERSITY, SUMY, UKRAINE., Ivakhniuk TV; SUMY STATE UNIVERSITY, SUMY, UKRAINE., Plakhtiienko IO; SUMY STATE UNIVERSITY, SUMY, UKRAINE., Smiianov YV; SUMY STATE UNIVERSITY, SUMY, UKRAINE., Hornostaieva PO; SUMY STATE UNIVERSITY, SUMY, UKRAINE. |
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Jazyk: | angličtina |
Zdroj: | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego [Pol Merkur Lekarski] 2023; Vol. 51 (1), pp. 42-47. |
DOI: | 10.36740/Merkur202301106 |
Abstrakt: | Objective: Aim: To study the species composition of microorganisms isolated from patients with otomycosis, and to control the sensitivity of isolated microorganisms to the most commonly used antifungal drugs. Patients and Methods: Materials and methods: The main group of study was 132 patients with a preliminary diagnosis of Otomycosis was carried out in the period 2020-2022.To study the sensitivity of isolated microorganisms to antifungal drugs, the Himedia paper disk method (India) was used. Results: Results: Analysis of studies showed that among 132 patients, fungal infection was found in 101 patients (76%), the cultural method - in 31 patients (23.5%); of them women - 56 (42.4%), men - 60 (45.5%) aged 16 to 76; children - 16 (12.1%) aged 6 to 12 years. However, among all patients (n = 132) with otomycosis, fungal lesions of the outer ear prevail, which were detected in 85 (64.4%) patients, that is, fungal otitis was detected in 47 (35.6%). Conclusion: Conclusions: The general structure of the species spectrum of etiologically significant pathogens of otomycosis: Candida spp. (78.0%) of the total spectrum of isolates. The sensitivity of isolated micromycetes to antifungal drugs varied in different fungal species and in different antifungal drugs. |
Databáze: | MEDLINE |
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