Plant Protein-Peptide Supramolecular Polymers with Reliable Tissue Adhesion for Surgical Sealing.
Autor: | Nie J; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun, 130012, P. R. China., Sun Y; Department of Orthopedics, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Jilin Province, 130014, P. R. China., Cheng X; Department of Orthopedics, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Jilin Province, 130014, P. R. China., Wen G; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun, 130012, P. R. China., Liu X; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun, 130012, P. R. China., Cheng M; Department of Orthopedics, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Jilin Province, 130014, P. R. China., Zhao J; Department of Orthopedics, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Jilin Province, 130014, P. R. China., Li W; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun, 130012, P. R. China. |
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Jazyk: | angličtina |
Zdroj: | Advanced healthcare materials [Adv Healthc Mater] 2023 Aug; Vol. 12 (20), pp. e2203301. Date of Electronic Publication: 2023 Apr 10. |
DOI: | 10.1002/adhm.202203301 |
Abstrakt: | The fusion of protein science and peptide science opens up new frontiers in creating innovative biomaterials. Herein, a new kind of adhesive soft materials based on a natural occurring plant protein and short peptides via a simple co-assembly route are explored. The hydrophobic zein is supercharged by sodium dodecyl sulfate to form a stable protein colloid, which is intended to interact with charge-complementary short peptides via multivalent ionic and hydrogen bonds, forming adhesive materials at macroscopic level. The adhesion performance of the resulting soft materials can be fine-manipulated by customizing the peptide sequences. The adhesive materials can resist over 78 cmH (© 2023 Wiley-VCH GmbH.) |
Databáze: | MEDLINE |
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