Emphysematous pyelonephritis necessitating bilateral radical nephrectomy: A case report and literature review.

Autor: Wamsley CE; Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, United States., Morton A; Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, United States., Roth CG; Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA, United States., Izes JK; Department of Urology, Thomas Jefferson University Hospital, Philadelphia, PA, United States., Li L; Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
Jazyk: angličtina
Zdroj: Urology case reports [Urol Case Rep] 2023 Mar 07; Vol. 47, pp. 102376. Date of Electronic Publication: 2023 Mar 07 (Print Publication: 2023).
DOI: 10.1016/j.eucr.2023.102376
Abstrakt: Emphysematous pyelonephritis (EPN) is a severe, acute necrotizing infection of the kidney with gas accumulation in the renal parenchyma, collecting ducts, and/or perirenal tissue. We report a case of EPN in a 66 year-old male with uncontrolled diabetes mellitus (DM), urinary tract infection and septic shock necessitating emergent bilateral radical nephrectomy. Morphologically, the kidney parenchyma revealed severe acute bacterial pyelonephritis with extensive abscesses, gas cysts, necrosis and foci of infarctions. The uninvolved background cortex parenchyma exhibited diabetic nephropathy (DN), Class IIB. Post-operatively, the patient remained dialysis-dependent with multiple re-admissions for recurrent multi-drug resistant E. coli pyocystitis, anemia and urinary retention.
Competing Interests: Christine E. Wamsley reports compensation for consultation services provided to Innovative Optics (Sarasota, FL) for research studies outside of the submitted work. The remaining authors have no financial interests to disclose.
(© 2023 The Authors. Published by Elsevier Inc.)
Databáze: MEDLINE
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