Feasibility of using counts-per-volume approach with a new SPECT phantom to optimize the relationship between administered dose and acquisition time.

Autor: Ichikawa H; Department of Radiology, Toyohashi Municipal Hospital, 50 Aza Hachiken Nishi, Aotake-Cho, Toyohashi, Aichi, 4418570, Japan.; Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 9200942, Japan., Shibutani T; Department of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 9200942, Japan., Shimada H; Department of Radiology, Toyohashi Municipal Hospital, 50 Aza Hachiken Nishi, Aotake-Cho, Toyohashi, Aichi, 4418570, Japan., Okuda K; Department of Radiation Science, Hirosaki University Graduate School of Health Sciences, 66-1 Honcho, Hirosaki, Aomori, 0368564, Japan., Kato T; Department of Radiology, Toyohashi Municipal Hospital, 50 Aza Hachiken Nishi, Aotake-Cho, Toyohashi, Aichi, 4418570, Japan., Nosaka H; Department of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 9200942, Japan.; Clinical Imaging Center for Healthcare, Nippon Medical School, 1-12-15 Sendagi, Bunkyo, Tokyo, 1130022, Japan., Nagaki A; Department of Radiological Technology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki, Okayama, 7108602, Japan., Onoguchi M; Department of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 9200942, Japan. onoguchi@staff.kanazawa-u.ac.jp.
Jazyk: angličtina
Zdroj: Radiological physics and technology [Radiol Phys Technol] 2023 Jun; Vol. 16 (2), pp. 244-253. Date of Electronic Publication: 2023 Mar 23.
DOI: 10.1007/s12194-023-00713-6
Abstrakt: We developed a phantom for single-photon emission computed tomography (SPECT), with the objective of assessing image quality to optimize administered dose and acquisition time. We investigated whether the concept of counts-per-volume (CPV), which is used as a predictor of visual image quality in positron emission tomography, can be used to estimate the acquisition time required for each SPECT image. QIRE phantoms for the head (QIRE-h) and torso (QIRE-t) were developed to measure four physical indicators of image quality in a single scan: uniformity, contrast of both hot and defective lesions with respect to the background, and linearity between radioactivity concentration and count density. The target organ's CPV (TCPV), sharpness index (SI), and contrast-to-noise ratio (CNR) were measured for QIRE-h and QIRE-t phantoms, and for anthropomorphic brain and torso phantoms. The SPECT image quality of the four phantoms was visually assessed on a 5-point scale. The acquisition time and TCPV were correlated for all four phantoms. The SI and CNR values were nearly identical for the QIRE and anthropomorphic phantoms with comparable TCPV. The agreement between the visual scores of QIRE-h and brain phantoms, as well as QIRE-t and torso phantoms, was moderate and substantial, respectively. Comparison of SPECT image quality between QIRE and anthropomorphic phantoms revealed close agreement in terms of physical indicators and visual assessments. Therefore, the TCPV concept can also be applied to SPECT images of QIRE phantoms, and optimization of imaging parameters for nuclear medicine examinations may be possible using QIRE phantoms alone.
(© 2023. The Author(s), under exclusive licence to Japanese Society of Radiological Technology and Japan Society of Medical Physics.)
Databáze: MEDLINE