Importance of moderate-to-vigorous physical activity during the COVID-19 pandemic: a systematic review and meta-analysis.

Autor:	Rejeki PS; Department of Medical Physiology and Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Witarto BS; Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Witarto AP; Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Rifdah SN; Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Wafa IA; Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Utami DM; Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Izzatunnisa N; Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Kencono Wungu CD; Department of Medical Physiology and Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Khaerunnisa S; Department of Medical Physiology and Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Sakina; Department of Anatomy, Histology and Pharmacology, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia., Fazleen Mohd Fathil NE; International Medical School, Management and Science University, Shah Alam, Selangor Darul Ehsan, Malaysia.
Jazyk:	angličtina
Zdroj:	Journal of basic and clinical physiology and pharmacology [J Basic Clin Physiol Pharmacol] 2023 Mar 24; Vol. 34 (3), pp. 311-320. Date of Electronic Publication: 2023 Mar 24 (Print Publication: 2023).
DOI:	10.1515/jbcpp-2023-0040
Abstrakt:	Moderate-to-vigorous physical activity (MVPA) has been shown to have a favorable effect on many diseases as a complementary therapy and is a critical component of healthy living. During the pandemic era, physical activity has been promoted for resistance against coronavirus disease 2019 (COVID-19). However, there is scarce evidence on whether MVPA could reduce the infectivity and susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The objective of this meta-analysis was to determine the effect of MVPA on morbidity, mortality, and duration of hospitalization in COVID-19 patients. We performed a comprehensive search of five online databases for eligible studies up to September 9, 2021. Meta-analyses were conducted to determine the association between MVPA and COVID-19-related morbidity, hospitalization, and mortality. The odds ratio (OR) was applied as the summary statistic for the primary outcomes. Secondary analyses were conducted to evaluate the difference in the metabolic equivalent of tasks (METs) between the outcome and non-outcome groups with the mean difference as the pooled effect. This meta-analysis included eight observational studies. We found that MVPA significantly reduced the odds of contracting SARS-CoV-2 infection (OR=0.88; 95% confidence interval [CI] = 0.85-0.92), hospitalization (OR=0.56; 95% CI=0.35-0.92), and mortality (OR=0.42; 95% CI=0.21-0.81) due to COVID-19 compared to no physical activity. METs≥500 min/week were linked to decreased morbidity and mortality of COVID-19 (OR=0.94 [95% CI=0.90-0.98]; OR=0.56 [95% CI=0.38-0.83]). COVID-19 patients with MVPA demonstrated a lower risk of COVID-19-related morbidity, hospitalization, and mortality compared to those who were less active, highlighting the importance of an active lifestyle despite the pandemic situation where such activities are limited. (© 2023 Walter de Gruyter GmbH, Berlin/Boston.)
Databáze:	MEDLINE
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