Fulminant Guillain-Barré syndrome secondary to Campylobacter coli infection: An autopsy case report.

Autor:	Kutsuna F; Department of Neurology, National Hospital Organization Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-0835, Japan., Soeda M; Department of Pathology, National Hospital Organization Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-0835, Japan., Hibino A; Department of Emergency, National Hospital Organization Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-0835, Japan., Tokuda M; Department of Neurology, National Hospital Organization Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-0835, Japan., Miura S; Department of Pathology, National Hospital Organization Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-0835, Japan., Iwanaga H; Department of Neurology, National Hospital Organization Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-0835, Japan.
Jazyk:	angličtina
Zdroj:	ENeurologicalSci [eNeurologicalSci] 2023 Feb 25; Vol. 31, pp. 100454. Date of Electronic Publication: 2023 Feb 25 (Print Publication: 2023).
DOI:	10.1016/j.ensci.2023.100454
Abstrakt:	The most common infection preceding Guillain-Barré syndrome (GBS) is Campylobacter jejuni enteritis, although a few patients present with Campylobacter coli . We report a case of C. coli -induced fulminant GBS. A 61-year-old woman presented with bilateral limb weakness. Nerve conduction studies revealed a reduction of amplitude and C. coli was isolated from a fecal specimen, leading to the diagnosis of GBS. Although the patient was immediately administered immunoglobulin, her symptoms rapidly worsened and she died. Peripheral nerve autopsy revealed myelin ovoid, and infiltration of CD68-positive macrophages into nerves. More effective treatments for fulminant GBS need to be developed. Competing Interests: None. (© 2023 The Authors.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu