Micro- and nanoplastic toxicity: A review on size, type, source, and test-organism implications.

Autor: Pelegrini K; Escola Politécnica, Pontifícia Universidade Católica do Rio Grande Do Sul (PUCRS). Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil; Programa de Engenharia e Tecnologia de Materiais, Escola Politécnica, PUCRS, Av. Ipiranga, 6690, CEP: 90610-000 Porto Alegre, RS, Brazil. Electronic address: kaue.pelegrini@edu.pucrs.br., Pereira TCB; Laboratório de Biologia Genômica e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS). Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil; Programa de Medicina e Ciências da Saúde, Escola de Medicina, PUCRS, Av. Ipiranga, 6690, CEP: 90610-000 Porto Alegre, RS, Brazil. Electronic address: talita.pereira@edu.pucrs.br., Maraschin TG; Escola Politécnica, Pontifícia Universidade Católica do Rio Grande Do Sul (PUCRS). Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil; Programa de Engenharia e Tecnologia de Materiais, Escola Politécnica, PUCRS, Av. Ipiranga, 6690, CEP: 90610-000 Porto Alegre, RS, Brazil. Electronic address: thuany.maraschin@acad.pucrs.br., Teodoro LS; Laboratório de Biologia Genômica e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS). Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil; Programa de Biologia Celular e Molecular, Escola de Ciências da Saúde e da Vida, PUCRS, Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil., Basso NRS; Escola Politécnica, Pontifícia Universidade Católica do Rio Grande Do Sul (PUCRS). Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil; Programa de Engenharia e Tecnologia de Materiais, Escola Politécnica, PUCRS, Av. Ipiranga, 6690, CEP: 90610-000 Porto Alegre, RS, Brazil., De Galland GLB; Instituto de Química, Universidade Federal Do Rio Grande Do Sul (UFRGS), Av. Bento Gonçalves, 9500, CEP: 91570-970 Porto Alegre, RS, Brazil. Electronic address: griselda.barrera@ufrgs.br., Ligabue RA; Escola Politécnica, Pontifícia Universidade Católica do Rio Grande Do Sul (PUCRS). Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil; Programa de Engenharia e Tecnologia de Materiais, Escola Politécnica, PUCRS, Av. Ipiranga, 6690, CEP: 90610-000 Porto Alegre, RS, Brazil. Electronic address: rligabue@pucrs.br., Bogo MR; Laboratório de Biologia Genômica e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS). Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil; Programa de Medicina e Ciências da Saúde, Escola de Medicina, PUCRS, Av. Ipiranga, 6690, CEP: 90610-000 Porto Alegre, RS, Brazil; Programa de Biologia Celular e Molecular, Escola de Ciências da Saúde e da Vida, PUCRS, Av. Ipiranga, 6681, CEP: 90619-900 Porto Alegre, RS, Brazil. Electronic address: mbogo@pucrs.br.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2023 Jun 20; Vol. 878, pp. 162954. Date of Electronic Publication: 2023 Mar 21.
DOI: 10.1016/j.scitotenv.2023.162954
Abstrakt: Polymeric wastes are among the current major environmental problems due to potential pollution and contamination. Within the spectrum of polymeric waste, microplastics (MPs) and nanoplastics (NPs) have gained ground in recent research since these particles can affect the local biota, inducing toxic effects on several organisms. Different outcomes have been reported depending on particle sizes, shape, types, and exposed organisms and conditions, among other variables. This review aimed to compile and discuss the current knowledge and possible literature gaps regarding the MPs and NPs generation and their toxicological effects as stressors, considering polymer type (as polyethylene, polypropylene, polyethylene terephthalate, polystyrene, polyvinyl chloride, or others), size (micro- or nano-scale), source (commercial, lab-synthesized, or environmental) and test organism group. In that sense, 615 publications were analyzed, among which 72 % discussed micro-sized plastics, while <28 % assayed the toxicity of NPs (<1 μm). For most polymers, MPs and NPs were commercially purchased and used without additional size reduction processes; except for polyethylene terephthalate studies that mostly used grinding and cutting methods to obtain MPs. Polystyrene (PS) was the main polymer studied, as both MPs and NPs. PS accounts for >90 % of NPs reports evaluated, reflecting a major literature gap if compared to its 35.3 % share on MPs studies. Among the main organisms, arthropods and fish combined accounted for nearly 40 % of toxicity testing. Overall, the different types of plastics showed a tendency to report toxic effects, except for the 'Survival/lethality' category, which might indicate that polymeric particles induce mostly sublethal toxic effects. Furthermore, despite differences in publication numbers, we observed greater toxicity reported for NPs than MPs with oxidative stress among the majorly investigated endpoints. This study allowed a hazard profile overview of micro/nanoplastics (MNPs) and the visualization of literature gaps, under a broad diversity of toxicological evidence.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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