| Autor: |
Li HW; Green Catalysis Center, and College of Chemistry, Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou, 450001, P. R. China., Luo YC; Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, China. xgzhang@mail.sioc.ac.cn., Yu LC; Green Catalysis Center, and College of Chemistry, Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou, 450001, P. R. China.; State Key Laboratory of Fluorinated Functional Membrane Materials, Zibo, 256401, China., Zhang X; Green Catalysis Center, and College of Chemistry, Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou, 450001, P. R. China.; Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, China. xgzhang@mail.sioc.ac.cn. |
| Abstrakt: |
A palladium-catalyzed gem -difluoroallylation of propargyl sulfonates with gem -difluoroallylboron has been developed. The reaction features synthetic simplicity and high functional group tolerance, affording 3,3-difluoro-skipped 1,5-enynes with high efficiency and regioselectivity. In particular, the resulting products can serve as versatile synthons for diversified transformations, having potential applications in medicinal chemistry. |
