Randomized controlled trial comparing open anterograde anatomic radical retropubic prostatectomy with retrograde technique.

Autor:	Carrerette FB; Department of Surgery (Urology), Pedro Ernesto University Hospital of State University of Rio de Janeiro, Rio de Janeiro, Brazil., Rodeiro DB; Department of Surgery (Urology), Pedro Ernesto University Hospital of State University of Rio de Janeiro, Rio de Janeiro, Brazil., Filho RTF; Department of Surgery (Urology), Pedro Ernesto University Hospital of State University of Rio de Janeiro, Rio de Janeiro, Brazil., Santos PA; Department of Surgery (Urology), Pedro Ernesto University Hospital of State University of Rio de Janeiro, Rio de Janeiro, Brazil., Lara CC; Department of Surgery (Urology), Pedro Ernesto University Hospital of State University of Rio de Janeiro, Rio de Janeiro, Brazil., Damião R; Department of Surgery (Urology), Pedro Ernesto University Hospital of State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Jazyk:	angličtina
Zdroj:	Asian journal of urology [Asian J Urol] 2023 Apr; Vol. 10 (2), pp. 151-157. Date of Electronic Publication: 2021 Nov 25.
DOI:	10.1016/j.ajur.2021.11.008
Abstrakt:	Objective: Radical prostatectomy is the recommended treatment for localized prostate cancer; however, it is an invasive procedure that can leave serious morbidity. Robot-assisted radical prostatectomy was introduced with the aim of reducing postoperative morbidity and facilitating rapid recovery compared to the traditional Walsh's open radical retropubic prostatectomy. Therefore, a protocol was developed to perform an open prostatectomy comparable to that performed by robotics, but without involving novel instrumentation. Methods: A total of 220 patients diagnosed with localized prostate cancer underwent radical prostatectomy. They were divided into two groups: anterograde technique (115 patients) and the retrograde method (105 patients). The study outcomes were observed 3 months after surgery. Results: No differences were found in terms of surgical time, hospital stay, and suction drainage. However, reduced bleeding was observed in the anterograde technique ( p =0.0003), with rapid anastomosis duration ( p =0.005). Among the patients, 60.9% undergoing the anterograde technique were continent 3 months after surgery compared to 42.9% treated by the retrograde method ( p =0.007). Additionally, fewer complications in terms of the number ( p =0.007) and severity ( p =0.0006) were observed in the anterograde technique. Conclusion: The anterograde method displayed increased efficiency in reducing complications, compared to the retrograde technique. Competing Interests: The authors declare no conflict of interest. (© 2022 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu