Incidence and case-fatality rate of stroke in General Villegas, Buenos Aires, Argentina. The EstEPA population study.

Autor: Ameriso SF; Departamento de Neurología. Fleni. Ciudad Autónoma de Buenos Aires, Argentina., Alet MJ; Departamento de Neurología. Fleni. Ciudad Autónoma de Buenos Aires, Argentina. Electronic address: malet@fleni.org.ar., Rosales J; Departamento de Neurología. Fleni. Ciudad Autónoma de Buenos Aires, Argentina., Rodríguez-Pérez MS; Departamento de Neurología. Fleni. Ciudad Autónoma de Buenos Aires, Argentina., Povedano GP; Departamento de Neurología. Fleni. Ciudad Autónoma de Buenos Aires, Argentina., Pujol-Lereis VA; Departamento de Neurología. Fleni. Ciudad Autónoma de Buenos Aires, Argentina., Rodríguez-Lucci F; Departamento de Neurología. Fleni. Ciudad Autónoma de Buenos Aires, Argentina., Dossi D; Departamento de Neurología. Fleni. Ciudad Autónoma de Buenos Aires, Argentina., González CD; Departamento de Farmacología, Facultad de Medicina, Instituto Universitario CEMIC. Ciudad Autónoma de Buenos Aires, Argentina., Melcon MO; Fundación para Investigaciones Neuroepidemiológicas, Junín. Buenos Aires, Argentina.
Jazyk: angličtina
Zdroj: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2023 May; Vol. 32 (5), pp. 107058. Date of Electronic Publication: 2023 Mar 20.
DOI: 10.1016/j.jstrokecerebrovasdis.2023.107058
Abstrakt: Objectives: Stroke epidemiology varies among different populations. The burden of stroke is high in low- and middle-income countries. Reliable population data is needed to assess the impact of stroke and to develop policies aimed to improve stroke care in our region. EstEPA is a population-based project assessing prevalence, incidence, mortality and burden of stroke in General Villegas Department, Buenos Aires, Argentina (pop=30,864 inhabitants). We determined incidence of stroke (first-ever and recurrent stroke) and stroke case-fatality rate from 2017 to 2020.
Methods: First-ever strokes, recurrent strokes and transient ischemic attacks were ascertained and case-fatality rate was obtained. Diagnoses were based on standard AHA/WHO definitions. Study population included all persons residing in General Villegas during the three-year period. Hospitals, households, nursing homes, death certificates and several overlapping sources were surveyed.
Results: We assessed 92,592 person-years. There were 155 cerebrovascular events aged 70 years (SD ± 13 years), of which 115 were first-ever strokes (74%), 21 recurrent strokes (13.5%) and 19 transient ischemic attacks (12.5%). The crude overall incidence rate of first-ever strokes was 124.2 per 100,000 population (86.9 per 100,000 [95% CI 58.5-115.2] when standardized by WHO World population and 109.7 per 100,000 [95% CI 89.7-129.8] when standardized by Argentine population) and 317.0 per 100,000 population in subjects older than 40 years. Case fatality rate at 30 days of first-ever strokes was 27%.
Conclusion: In this population-based comprehensive stroke epidemiological study in Argentina, first-ever stroke incidence in an urban population was 124.2 per 100,000 population (86.9 per 100,000 adjusted by the WHO World population). This is lower than the incidence in other countries in the region and similar to a recent incidence study in Argentina. It is also comparable to reported incidence in most middle- and high-income countries. Stroke case-fatality rate was comparable to other population-based Latin-American studies.
Competing Interests: Conflict of Interest Statement Dr. Ameriso received honoraria for lectures from Gador, Sanofi, Bayer, and Ferrer. Dr. Alet received consulting fees from Boehringer Ingelheim. Dra. Rosales, Dra. Dossi and Dr. Rodríguez-Lucci received payment for lectures from Boehringer Ingelheim. Dra. Pujol-Lereis received payment for lectures from Gador.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: