| Autor: |
Kayumov M; Department of Medical Science, Chonnam National University Graduate School, Gwangju, Korea.; Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital, Chonnam National University Hospital Medical School, Gwangju, Korea.; Extracorporeal Circulation Research Team, Chonnam National University Hospital, Gwangju, Korea., Habimana R; Extracorporeal Circulation Research Team, Chonnam National University Hospital, Gwangju, Korea.; Department of Biomedical Sciences, Chonnam National University Graduate School, Chonnam National University Medical School, Gwangju, Korea., Kim D; Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital, Chonnam National University Hospital Medical School, Gwangju, Korea.; Extracorporeal Circulation Research Team, Chonnam National University Hospital, Gwangju, Korea., Obiweluozor FO; Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital, Chonnam National University Hospital Medical School, Gwangju, Korea.; Extracorporeal Circulation Research Team, Chonnam National University Hospital, Gwangju, Korea., Jeong IS; Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital, Chonnam National University Hospital Medical School, Gwangju, Korea.; Extracorporeal Circulation Research Team, Chonnam National University Hospital, Gwangju, Korea., Cho HJ; Extracorporeal Circulation Research Team, Chonnam National University Hospital, Gwangju, Korea.; Department of Pediatrics, Chonnam National University Children's Hospital and Chonnam National University Medical School, Gwangju, Korea. |
| Abstrakt: |
Extracorporeal membrane oxygenation (ECMO) use has remarkably increased in recent years. Although ECMO has become essential for patients with refractory cardiac and respiratory failure, extracorporeal circulation (ECC) is associated with significant complications. Small-animal models of ECC have been developed and widely used to better understand ECC-induced pathophysiology. This review article summarizes the development of small-animal ECC models, including the animal species, circuit configuration, priming, perioperative procedures, cannulation, and future perspectives of small-animal ECMO models. |
