Changes in Pulmonary Functions of Adolescents with Pectus Excavatum Throughout the Nuss Procedure.

Autor: Dreher C; Department of Pediatric Allergy, Children's Hospital, University of Bonn, Bonn, Germany., Reinsberg M; Department of Pediatric Allergy, Children's Hospital, University of Bonn, Bonn, Germany., Oetzmann von Sochaczewski C; Department of Pediatric Surgery, Children's Hospital, University of Bonn, Bonn, Germany., Siebert S; Department of Pediatric Allergy, Children's Hospital, University of Bonn, Bonn, Germany., Strohm J; Department of Pediatric Surgery, Children's Hospital, University of Bonn, Bonn, Germany., Kurz R; Department of Pediatric Surgery, Children's Hospital, University of Bonn, Bonn, Germany., Ziegler AM; Department of Pediatric Surgery, Children's Hospital, University of Bonn, Bonn, Germany., Heydweiller A; Department of Pediatric Surgery, Children's Hospital, University of Bonn, Bonn, Germany., Yavuz ST; Department of Pediatric Allergy, Children's Hospital, University of Bonn, Bonn, Germany. Electronic address: styavuz@yahoo.com.
Jazyk: angličtina
Zdroj: Journal of pediatric surgery [J Pediatr Surg] 2023 Sep; Vol. 58 (9), pp. 1674-1678. Date of Electronic Publication: 2023 Feb 28.
DOI: 10.1016/j.jpedsurg.2023.02.057
Abstrakt: Background: We aimed to determine the longitudinal changes in pulmonary functions of adolescents with Pectus Excavatum who underwent the Nuss procedure, the minimally invasive repair of pectus excavatum (MIRPE).
Methods: Lung function measurements were performed before bar implantation (T 0 ), at least six weeks to ten months after implantation (T 1a ), at least eleven months to sixty-one months after bar implantation (T 1b ) and at least two weeks after bar explantation (T 2 ).
Results: Data of 114 patients (83.3% male) whose median age at implantation was 15.6 years and at explantation 18.7 years were analyzed. Shortly after implantation at T 1a a significant decline of vital capacity (VC; n = 82), forced vital capacity (FVC; n = 78) and forced expiratory volume in 1 second (FEV 1 ; n = 80) compared to T 0 was seen. At T 1b a significant decline for the residual volume (RV; n = 83), the residual volume/total lung capacity ratio (RV/TLC; n = 81), the total specific airway resistance (sRaw; n = 80) and the total airway resistance (Raw; n = 84) also compared to T 0 was measured. In the comparison of T 1 b to T 2 a significant increase of VC, FVC (n = 67), FEV 1 (n = 69), TLC (n = 67) and a significant decrease of Raw (n = 66), sRaw, RV (n = 65) and the RV/TLC (n = 64) ratio could be observed. In the direct analysis between T 0 and T 2 , after the explantation of the bar a significant increase in VC (n = 54), FVC (n = 52), and TLC (n = 55) and a significant decrease of RV (n = 51) and the RV/TLC index (n = 50), and in airway resistance parameters like Raw (n = 52) and sRaw (n = 51) could be detected.
Conclusions: Lung function values along with markers of airway resistance improve in patients after the complete procedure of MIRPE.
Level of Evidence: Level II.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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