Microorganisms isolated in patients with post-cardiac surgery mediastinitis at a cardiology hospital of Mexico City.
| Autor: | Jiménez-González MDC; High Specialty Medical Unit, Cardiology Hospital, Centro Médico Nacional Siglo XXI., Mejía-Aguirre B; High Specialty Medical Unit, Cardiology Hospital, Centro Médico Nacional Siglo XXI., Ascencio-Montiel IJ; Epidemiological Surveillance Coordination. Instituto Mexicano del Seguro Social, Mexico City, Mexico. |
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| Jazyk: | angličtina |
| Zdroj: | Gaceta medica de Mexico [Gac Med Mex] 2023; Vol. 159 (1), pp. 17-23. |
| DOI: | 10.24875/GMM.M22000730 |
| Abstrakt: | Introduction: Mediastinitis after cardiovascular surgery gives rise to prolonged hospital stay and increased medical care costs, and is associated with high in-hospital mortality. Objective: To describe the clinical characteristics of patients with post-surgical mediastinitis, including the isolated microorganisms, resistance profile, and in-hospital survival. Methods: Cross-sectional study of patients with bacteriologically-confirmed post-surgical mediastinitis cared for at a cardiology hospital in Mexico City between January 2017 and March 2019. Results: Fifty-eight cases of mediastinitis were included. Median age was 67 years. Most subjects were males who underwent myocardial revascularization. During in-hospital follow-up, all-cause and mediastinitis-related mortality were 27.6% and 20.7%, respectively. Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli were the most commonly isolated microorganisms. High resistance to methicillin was found in coagulase-negative staphylococci, as well as high expression of extended-spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae strains. Conclusions: High mortality and significant antimicrobial resistance were found in patients with post-cardiac surgery mediastinitis. (Copyright: © 2023 Permanyer.) |
| Databáze: | MEDLINE |
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