Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Drug-Resistant Epilepsy in the MORE Multicenter Patient Registry.

Autor:	Peltola J; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands. jukka.peltola@tuni.fi., Colon AJ; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Pimentel J; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Coenen VA; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Gil-Nagel A; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Gonçalves Ferreira A; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Lehtimäki K; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Ryvlin P; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Taylor RS; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Ackermans L; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Ardesch J; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Bentes C; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Bosak M; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Burneo JG; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Chamadoira C; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Elger CE; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Erőss L; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Fabo D; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Faulkner H; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Gawlowicz J; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Gharabaghi A; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Iacoangeli M; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Janszky J; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Järvenpää S; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Kaufmann E; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Kho KH; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Kumlien E; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Laufs H; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Lettieri C; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Linhares P; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Noachtar S; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Parrent A; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Pataraia E; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Patel NK; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Peralta AR; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Rácz A; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Campos AR; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Rego R; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Ricciuti RA; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Rona S; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Rouhl RPW; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Schulze-Bonhage A; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Schuurman R; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Sprengers M; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Sufianov A; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Temel Y; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Theys T; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Van Paesschen W; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Van Roost D; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Vaz R; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Vonck K; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Wagner L; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Zwemmer J; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Abouihia A; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Brionne TC; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Gielen F; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands., Boon PAJM; From the Department of Neurology (J. Peltola, S.J.), Tampere University and Tampere University Hospital, Finland; Academic Center for Epileptology Kempenhaeghe/MUMC+ (A.J.C., L.A., R.P.W.R., L.W.), Maastricht, the Netherlands; Department of Neurosciences and Mental Health (J. Pimentel), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Department of Stereotactic and Functional Neurosurgery (V.A.C.), Universitätsklinikum Freiburg, Germany; Neurology Department (A.G.-N.), Epilepsy Program, Hospital Ruber Internacional, Madrid, Spain; Department of Neurosurgery (A.G.F., A.R.C.), Hospital Santa Maria Centro Hospitalar Lisboa Norte, Portugal; Department of Neurosurgery (K.L.), Tampere University Hospital and Tampere University, Finland; Département des Neurosciences Cliniques (P.R.), centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics (R.S.T.), Institute of Health and Well Being, University of Glasgow; College of Medicine and Health (R.S.T.), University of Exeter, United Kingdom; Departments of Neurosurgery (L.A., Y.T.), Maastricht University Medical Center, the Netherlands; Stichting Epilepsie Instellingen Nederland (SEIN) (J.A.), Zwolle; Neurophysiology Monitoring Unit (C.B.), Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Faculdade de Medicina (C.B., A.R.P.), Universidade de Lisboa, Portugal; Department of Neurology (M.B.), Jagiellonian University Medical College, Faculty of Medicine, Krakow, Poland; Western University (J.G.B., A.P.), London, Ontario, Canada; Neurosurgery Department (C.C., P.L., R.V.), Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Epileptology (C.E.E., A.R.), University Hospital Bonn, Germany; National Institute of Clinical Neuroscience (L.E.); Országos Idegtudományi Intézet/National Institute of Neurosciences (D.F.), Budapest, Hungary; North Bristol NHS Trust (H.F.), Bristol, United Kingdom; Wojewodzki Szpital Specjalistyczny w Lublinie (J.G.), Poland; Institute for Neuromodulation and Neurotechnology (A.G.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurosurgery (M.I.), Umberto I General University Hospital, Università Politecnica delle Marche, Ancona, Italy; Department of Neurology (J.J.), Medical School, University of Pécs, Hungary; Department of Neurology (E. Kaufmann), Ludwig Maximilians University, Munich, Germany; Medisch Spectrum Twente (MST) (K.H.K.), Enschede, the Netherlands; Department of Neuroscience (E. Kumlien), Uppsala University, Sweden; Klinik für Neurologie (H.L.), Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität zu Kiel, Germany; Neurology and Clinical Neurophysiology Unit (C.L.), Department of Neuroscience, 'S. Maria della Misericordia' University Hospital, Udine, Italy; Klinikum der Universität München (S.N.), Großhadern Neurologische Klinik und Poliklinik, Germany; Medizinische Universität Wien (E.P.), Austria; Southmead Hospital (N.K.P.), North Bristol NHS Trust, United Kingdom; Laboratory of EEG/Sleep (A.R.P.), Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Portugal; Neurophysiology Unit (R.R.), Neurology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; Department of Neurosurgery (R.A.R.), Viterbo Hospital, Italy; Epilepsy Unit (S.R.), Department of Neurosurgery and Neurotechnology, University of Tübingen, Germany; Department of Neurology (R.P.W.R.), Maastricht University Medical Centre+; School for Mental Health and Neurosciences (R.P.W.R.), Maastricht University, the Netherlands; University Hospital Freiburg (A.S.-B.), Germany; Amsterdam University Medical Center (R.S.), the Netherlands; Department of Neurology (M.S.), Ghent University Hospital, Ghent University, Belgium; Federal Centre of Neurosurgery (Tyumen) (A.S.), I.M. Sechenov First Moscow State Medical University, Moscow, Russia; UZ Leuven (T.T.); Department of Neurology (W.V.P.), UZ Leuven; Laboratory for Epilepsy Research (W.V.P.), KU Leuven; Department of Neurosurgery (D.V.R.), and Department of Neurology (K.V., P.A.J.M.B.), Ghent University Hospital, Ghent University, Belgium; Stichting Epilepsie Instellingen Nederland (SEIN) (J.Z.), Heemstede; Clinical Department (A.A., T.C.B.), Medtronic Internal Trading Sàrl, Tolochenaz, Switzerland; and Medtronic Bakken Research Center (F.G.), Maastricht, the Netherlands.
Jazyk:	angličtina
Zdroj:	Neurology [Neurology] 2023 May 02; Vol. 100 (18), pp. e1852-e1865. Date of Electronic Publication: 2023 Mar 16.
DOI:	10.1212/WNL.0000000000206887
Abstrakt:	Background and Objectives: The efficacy of deep brain stimulation of the anterior nucleus of the thalamus (ANT DBS) in patients with drug-resistant epilepsy (DRE) was demonstrated in the double-blind Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy randomized controlled trial. The Medtronic Registry for Epilepsy (MORE) aims to understand the safety and longer-term effectiveness of ANT DBS therapy in routine clinical practice. Methods: MORE is an observational registry collecting prospective and retrospective clinical data. Participants were at least 18 years old, with focal DRE recruited across 25 centers from 13 countries. They were followed for at least 2 years in terms of seizure frequency (SF), responder rate (RR), health-related quality of life (Quality of Life in Epilepsy Inventory 31), depression, and safety outcomes. Results: Of the 191 patients recruited, 170 (mean [SD] age of 35.6 [10.7] years, 43% female) were implanted with DBS therapy and met all eligibility criteria. At baseline, 38% of patients reported cognitive impairment. The median monthly SF decreased by 33.1% from 15.8 at baseline to 8.8 at 2 years ( p < 0.0001) with 32.3% RR. In the subgroup of 47 patients who completed 5 years of follow-up, the median monthly SF decreased by 55.1% from 16 at baseline to 7.9 at 5 years ( p < 0.0001) with 53.2% RR. High-volume centers (>10 implantations) had 42.8% reduction in median monthly SF by 2 years in comparison with 25.8% in low-volume center. In patients with cognitive impairment, the reduction in median monthly SF was 26.0% by 2 years compared with 36.1% in patients without cognitive impairment. The most frequently reported adverse events were changes (e.g., increased frequency/severity) in seizure (16%), memory impairment (patient-reported complaint, 15%), depressive mood (patient-reported complaint, 13%), and epilepsy (12%). One definite sudden unexpected death in epilepsy case was reported. Discussion: The MORE registry supports the effectiveness and safety of ANT DBS therapy in a real-world setting in the 2 years following implantation. Classification of Evidence: This study provides Class IV evidence that ANT DBS reduces the frequency of seizures in patients with drug-resistant focal epilepsy. Trial Registration Information: MORE ClinicalTrials.gov Identifier: NCT01521754, first posted on January 31, 2012. (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.)
Databáze:	MEDLINE
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