Biomimetic cell membrane-coated poly(lactic- co -glycolic acid) nanoparticles for biomedical applications.
Autor: | Jan N; Akson College of Pharmacy Mirpur University of Science and Technology (MUST) Mirpur Pakistan.; Department of Pharmaceutics, Faculty of Pharmacy The Islamia University of Bahawalpur Bahawalpur Pakistan., Madni A; Department of Pharmaceutics, Faculty of Pharmacy The Islamia University of Bahawalpur Bahawalpur Pakistan., Khan S; Department of Pharmaceutics, Faculty of Pharmacy The Islamia University of Bahawalpur Bahawalpur Pakistan., Shah H; Department of Pharmaceutics, Faculty of Pharmacy The Islamia University of Bahawalpur Bahawalpur Pakistan., Akram F; Department of Pharmaceutics, Faculty of Pharmacy The Islamia University of Bahawalpur Bahawalpur Pakistan., Khan A; Department of Pharmaceutics, Faculty of Pharmacy The Islamia University of Bahawalpur Bahawalpur Pakistan., Ertas D; Department of Biomedical Engineering Erciyes University Kayseri Turkey., Bostanudin MF; College of Pharmacy Al Ain University Abu Dhabi United Arab Emirates.; AAU Health and Biomedical Research Center Al Ain University Abu Dhabi United Arab Emirates., Contag CH; Department of Microbiology and Molecular Genetics Michigan State University East Lansing Michigan USA.; Institute for Quantitative Health Science and Engineering (IQ) and Department of Biomedical Engineering (BME) Michigan State University East Lansing Michigan USA., Ashammakhi N; Institute for Quantitative Health Science and Engineering (IQ) and Department of Biomedical Engineering (BME) Michigan State University East Lansing Michigan USA.; Department of Bioengineering University of California, Los Angeles Los Angeles California USA., Ertas YN; Department of Biomedical Engineering Erciyes University Kayseri Turkey.; ERNAM-Nanotechnology Research and Application Center Erciyes University Kayseri Turkey.; UNAM-National Nanotechnology Research Center Bilkent University Ankara Turkey. |
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Jazyk: | angličtina |
Zdroj: | Bioengineering & translational medicine [Bioeng Transl Med] 2022 Nov 02; Vol. 8 (2), pp. e10441. Date of Electronic Publication: 2022 Nov 02 (Print Publication: 2023). |
DOI: | 10.1002/btm2.10441 |
Abstrakt: | Poly(lactic- co -glycolic acid) (PLGA) nanoparticles (NPs) are commonly used for drug delivery because of their favored biocompatibility and suitability for sustained and controlled drug release. To prolong NP circulation time, enable target-specific drug delivery and overcome physiological barriers, NPs camouflaged in cell membranes have been developed and evaluated to improve drug delivery. Here, we discuss recent advances in cell membrane-coated PLGA NPs, their preparation methods, and their application to cancer therapy, management of inflammation, treatment of cardiovascular disease and control of infection. We address the current challenges and highlight future research directions needed for effective use of cell membrane-camouflaged NPs. Competing Interests: The authors declare no conflict of interest. (© 2022 The Authors. Bioengineering & Translational Medicine published by Wiley Periodicals LLC on behalf of American Institute of Chemical Engineers.) |
Databáze: | MEDLINE |
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