Central Retinal Artery Occlusion in a Young Patient With a Hidden Unusual Sickle Cell Trait.

Autor: Semidey VA; Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, SAU., Magliyah MS; Department of Ophthalmology, Prince Mohammed Medical City, Aljouf, SAU., Alali N; Ophthalmology Division, Department of Surgery, Faculty of Medicine, University of Tabuk, Tabuk, SAU., Hashem F; Ophthalmology Division, Department of Surgery, Faculty of Medicine, University of Tabuk, Tabuk, SAU., ALBalawi HB; Ophthalmology Division, Department of Surgery, Faculty of Medicine, University of Tabuk, Tabuk, SAU.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2023 Feb 11; Vol. 15 (2), pp. e34865. Date of Electronic Publication: 2023 Feb 11 (Print Publication: 2023).
DOI: 10.7759/cureus.34865
Abstrakt: Sickle cell trait is considered a benign condition. Ophthalmic manifestations are infrequent but can result in significant visual deterioration. We present a case of a 33-year-old male, not known to have any medical illnesses, who presented to the ophthalmological emergency room complaining of a sudden onset of painless and profound left eye vision loss for 12 hours. The patient denied any medication use, past eye trauma, or surgery. On detailed ophthalmologic examination, the best-corrected visual acuity (BCVA) was 20/20 in the right eye and hand movement in the left eye. Dilated fundus examination of the left eye showed a central retinal artery occlusion (CRAO) with pale, white retinal swelling and a macular cherry-red spot. Fundus fluorescein angiography showed delayed arterial filling with persistently reduced macular perfusion. CRAO was diagnosed in an otherwise healthy young male. Systemic workup was negative except for protein electrophoresis, which showed sickle cell trait, and HbA1C was 7.8%. Later, atrophic macular changes with a pale optic disc were observed, and BCVA was reduced to light perception. CRAO in young patients amounts to diverse causes, which require extensive systemic workup. In addition, the concurrence of the sickle cell trait with diabetes mellitus might have a role in CRAO development.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Semidey et al.)
Databáze: MEDLINE