Effect of nano-ceramic coating on surface property and microbial adhesion to poly(methyl methacrylate).

Autor: Yang B; Department of Restorative Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, Illinois, USA., Ginsburg S; Department of Restorative Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, Illinois, USA., Li W; Department of Pediatric Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, Illinois, USA., Vilela MM; Department of Pediatric Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, Illinois, USA., Shahmohammadi M; Department of Chemical Engineering, College of Engineering, University of Illinois Chicago, Chicago, Illinois, USA., Takoudis CG; Department of Chemical Engineering, College of Engineering, University of Illinois Chicago, Chicago, Illinois, USA.; Department of Biomedical Engineering, College of Engineering, University of Illinois Chicago, Chicago, Illinois, USA., Wu CD; Department of Pediatric Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, Illinois, USA.
Jazyk: angličtina
Zdroj: Journal of biomedical materials research. Part B, Applied biomaterials [J Biomed Mater Res B Appl Biomater] 2023 Aug; Vol. 111 (8), pp. 1480-1487. Date of Electronic Publication: 2023 Mar 15.
DOI: 10.1002/jbm.b.35247
Abstrakt: To improve surface properties of poly(methyl methacrylate) (PMMA) using nano-ceramic coatings and assess microbial adherence after long-term use of a chemical cleanser. Thirty-six PMMA samples were fabricated, polished and coated with a nano-thin TiO 2 or mixed TiO 2 /ZrO 2 , with uncoated samples as controls. Six samples in each group (n = 12) were soaked in Polident denture cleaner 180 times for 30 min, while six were soaked in deionized water. Surface roughness of PMMA before and after being soaked in Polident was assessed. All samples were subsequently exposed to Candida albicans for 6 h and the adherent cells were determined by viable colony count. Two-way analysis of variance was performed for statistical analysis. No significant difference in surface roughness was noted between the uncoated and coated PMMA before soaking. After soaking, surface roughness of the uncoated PMMA increased from 0.164 to 0.532 μm (p < .05). No significant change was observed for TiO 2 -coated (0.105-0.143 μm) or TiO 2 /ZrO 2 -coated PMMA (0.104-0.141 μm). Attachment of C. albicans to PMMA soaked in water showed significantly less attachment to both TiO 2 -coated (1.4 × 10 3 cfu/ml) and TiO 2 /ZrO 2 -coated PMMA (1.6 × 10 3 cfu/ml) than to the uncoated PMMA (2.6 × 10 3 cfu/ml). After soaking in Polident, the uncoated PMMA had significantly less C. albicans attachment than coated samples. Less attachment was noted on the TiO 2 /ZrO 2 -coated PMMA then the TiO 2 -coated samples (p < .05). Nano-ceramic TiO2 2 /ZrO 2 coating of PMMA denture base material alters surface properties thus reduces oral microbial adhesion. It represents a promising alternative to the chemical disinfection for PMMA denture materials.
(© 2023 The Authors. Journal of Biomedical Materials Research Part B: Applied Biomaterials published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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