Nanoscale Probing of the Supramolecular Assembly in a Two-Component Gel by Near-Field Infrared Spectroscopy.

Autor: Chevigny R; Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box, Jyväskylä, 35, 40014 JYU, Finland., Sitsanidis ED; Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box, Jyväskylä, 35, 40014 JYU, Finland., Schirmer J; Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box, Jyväskylä, 35, 40014 JYU, Finland., Hulkko E; Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box, Jyväskylä, 35, 40014 JYU, Finland.; Department of Biological and Environmental Sciences, Nanoscience Center, University of Jyväskylä, P.O. Box, Jyväskylä, 35, 40014 JYU, Finland., Myllyperkiö P; Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box, Jyväskylä, 35, 40014 JYU, Finland., Nissinen M; Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box, Jyväskylä, 35, 40014 JYU, Finland., Pettersson M; Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box, Jyväskylä, 35, 40014 JYU, Finland.
Jazyk: angličtina
Zdroj: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Jun 07; Vol. 29 (32), pp. e202300155. Date of Electronic Publication: 2023 Apr 27.
DOI: 10.1002/chem.202300155
Abstrakt: The design of soft biomaterials requires a deep understanding of molecular self-assembly. Here a nanoscale infrared (IR) spectroscopy study of a two-component supramolecular gel is introduced to assess the system's heterogeneity and supramolecular assembly. In contrast to far-field IR spectroscopy, near-field IR spectroscopy revealed differences in the secondary structures of the gelator molecules and non-covalent interactions at three distinct nano-locations of the gel network. A β-sheet arrangement is dominant in single and parallel fibres with a small proportion of an α-helix present, while the molecular assembly derives from strong hydrogen bonding. However, at the crossing point of two fibres, only the β-sheet motif is observed, with an intense π-π stacking contribution. Near-field nanospectroscopy can become a powerful tool for the nanoscale distinction of non-covalent interactions, while it is expected to advance the existing spectroscopic assessments of supramolecular gels.
(© 2023 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.)
Databáze: MEDLINE
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