Quality improvement study on the effectiveness of intranasal povidone-iodine decolonization on surgery patients.

Autor:	Hammond EN; Institute for Clinical and Translational Research, University of Wisconsin-Madison, Madison, WI, 53705, USA.; Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA., Kates AE; Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, 53705, USA., Putman-Buehler N; Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison, Madison, WI53706, USA., Watson L; SSM Health, St. Mary's Hospital, Madison, WI, 53715, USA., Godfrey JJ; Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, 53705, USA., Riley CN; Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, 53705, USA., Dixon J; Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, 53705, USA., Brys N; Waisman Center, University of Wisconsin-Madison, 1500 Highland Avenue, Madison, WI, 53705, USA., Haleem A; Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA., Bentz ML; Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA., Safdar N; Division of Infectious Disease, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, 53705, USA.
Jazyk:	angličtina
Zdroj:	Infection prevention in practice [Infect Prev Pract] 2023 Feb 18; Vol. 5 (2), pp. 100274. Date of Electronic Publication: 2023 Feb 18 (Print Publication: 2023).
DOI:	10.1016/j.infpip.2023.100274
Abstrakt:	Background: Surgical site infection prevention and treatment remains a challenge in healthcare settings globally. The routine use of intranasal mupirocin for decolonization has challenges and preoperative intranasal povidone-iodine decolonization is another option. The purpose of this quality improvement study was to assess if a one-time preoperative intranasal povidone-iodine application could reduce the risk of the likelihood of nasal carriage of Staphylococcus aureus after surgery. Methods: Ambulatory Surgery Center patients were enrolled in an intranasal povidone-iodine decolonization quality improvement study as they reported at the pre-operative holding area. Pre-decolonization intranasal samples were collected, followed by intranasal application of povidone-iodine. Patients waited for a minimum of 20 minutes after application before proceeding with surgery. Nasal samples were again collected after surgery. Each sample was tested for S. aureus colonization using the 16S rRNA-mecA-nuc triplex polymerase chain reaction, standard biochemical tests, and qualitative culturing. Findings: In the 98 patients enrolled, 36% of these patients had intranasal colonization with S. aureus by 16S rRNA-mecA-nuc triplex polymerase chain reaction before surgery. Using a qualitative culture technique, 28% of patients tested positive for S. aureus before surgery and 20% of patients tested positive for S. aureus after surgery ( P  = 0.039). Conclusion: Intranasal preoperative povidone-iodine is an effective strategy in the decolonization of S. aureus from the nares if properly implemented. (© 2023 The Authors.)
Databáze:	MEDLINE
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